118288-08-7|LafutidineProducts Supply - Chemical intermediates Network

Lafutidine cas no:118288-08-7

Synonyms: Acetamide,2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-,(+)- (9CI);Acetamide,2-[(2-furanylmethyl)sulfinyl]-N-[4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-,(Z)-(+)-;(+)-2-(Furfurylsulfinyl)-N-[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]acetamide;(+)-Lafutidine;FRG 8813;Protecadin;Stogar;

Identification

NameLafutidine
CAS118288-08-7
SynonymsAcetamide,2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-,(+)- (9CI);Acetamide,2-[(2-furanylmethyl)sulfinyl]-N-[4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-,(Z)-(+)-;(+)-2-(Furfurylsulfinyl)-N-[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]acetamide;(+)-Lafutidine;FRG 8813;Protecadin;Stogar;
Molecular FormulaC₂₂H₂₉N₃O₄S
Molecular Weight431.55

Chemical Properties

AppearanceYellowish white crystalline powder
refractive index1.598

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD	oral	> 400mg/kg (400mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 417, 1995.
mouse	LD50	intravenous	47900ug/kg (47.9mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 143, 1995.
mouse	LD50	oral	1034mg/kg (1034mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 143, 1995.
rat	LD50	intravenous	84mg/kg (84mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 143, 1995.
rat	LD50	oral	1248mg/kg (1248mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 143, 1995.

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SUNWELL CHEMICALS CO.,LTD.(INTERPHARMA TRADING CO...: Tel:; Address: SUITE 1108,GOLDEN PLAZA,NO.118,QING CHUN ROAD,HANGZHOU,ZHEJIANG,CHINA

Shanghai Jinhong Bio-Pharmaceutical Technology Co...: Tel:+86-21-51996950; Address: Building A, No.688 Qiushi Road, Jinshan district, Shanghai, China

Zhejiang Medicines & Health Products Import & Exp...: Tel:; Address: ZMC Building,101-2 N. Zhongshan Road,Hangzhou,China.

Hangzhou Pharma & Chem Co.,Ltd.: Tel:+86-571-87040515; Address: Rm.1201,QinglianBldg.No,139QingchunRd,HangzhouCity,Zhejiang,China

Chemfar Ltd.: Tel:; Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China

Beijing J&R Times Technology Co., Ltd.: Tel:+86-10-64424939; Address: A1403,Rome garden, No.18, Huixin West Street, Chaoyang District, Beijing, China

Zhejiang Chempharm Industry & Trading Co., Ltd.: Tel:0086-571-87701568 87701600; Address: 12,lianhuafeng road,yuhuangshan, Hangzhou,China

SINOCO CHEMICAL CO., LIMITED: Tel:+86-571-81956191, 81956192; Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China.

J.INC.: Tel:+91 79 30903703; Address: 303, 3rd Floor, Royale Manor, Law Garden,Ellisbridge, Ahmedabad - 380006,Gujarat, India

Eagle Sky PharmaTech: Tel:; Address: Rm 323, Building 3, Yard A, No. 4, Yongding Rd Jia , Haidian

Cangzhou Goldlion Chemicals Co., Ltd.: Tel:+86-(317)-3200188; Address: 402-1, No.5th Building, Chaoyang Huayuan Area ,NO.32, Yuhe Road ,Cangzhou City, Hebei Province, PRC, Cangzhou, Hebei 061001,

Beijing Lunarsun Pharmaceutical Co., Ltd.: Tel:+86-(10)-80771328, 80771377; Address: C1-802, Yangguangguangchang, Anli Road No.68, Chaoyang District, Beijing 100101,

Shandong Hongfuda Pharma. Chem. Co., Ltd.: Tel:+86-(531)-88870807; Address: F Bldg. West Unit North Area of Univ. Tech. Garden Xinyu Rd., Shandong 250101,

Taizhou P&J International Trade Co., Ltd.: Tel:+86-(576)-86137488, 86137955; Address: 901 Room, Xingyuan Mansion, Wenling, Zhejiang 317500,

Chengdu Qiaofeng Technological Development Co., Ltd.: Tel:+86-(28)-85149048, 85149038; Address: Room 503, B, ChuangXin Center, GaoPeng Road , GaoXin Zone, ChengDu, SiChuan, ChengDu, SiChuan,

Lafutidine cas no:118288-08-7

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