118288-08-7|LafutidineProducts Supply - Chemical intermediates Network

Lafutidine cas no:118288-08-7

Synonyms: Acetamide,2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-,(+)- (9CI);Acetamide,2-[(2-furanylmethyl)sulfinyl]-N-[4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-,(Z)-(+)-;(+)-2-(Furfurylsulfinyl)-N-[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]acetamide;(+)-Lafutidine;FRG 8813;Protecadin;Stogar;

Identification

NameLafutidine
CAS118288-08-7
SynonymsAcetamide,2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-,(+)- (9CI);Acetamide,2-[(2-furanylmethyl)sulfinyl]-N-[4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-,(Z)-(+)-;(+)-2-(Furfurylsulfinyl)-N-[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]acetamide;(+)-Lafutidine;FRG 8813;Protecadin;Stogar;
Molecular FormulaC₂₂H₂₉N₃O₄S
Molecular Weight431.55

Chemical Properties

AppearanceYellowish white crystalline powder
refractive index1.598

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD	oral	> 400mg/kg (400mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 417, 1995.
mouse	LD50	intravenous	47900ug/kg (47.9mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 143, 1995.
mouse	LD50	oral	1034mg/kg (1034mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 143, 1995.
rat	LD50	intravenous	84mg/kg (84mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 143, 1995.
rat	LD50	oral	1248mg/kg (1248mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 143, 1995.

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SUNWELL CHEMICALS CO.,LTD.(INTERPHARMA TRADING CO...: Tel:; Address: SUITE 1108,GOLDEN PLAZA,NO.118,QING CHUN ROAD,HANGZHOU,ZHEJIANG,CHINA

Hangzhou Rongda Pharm & Chem Co, Ltd.: Tel:0571-28889928; Address: Xinqiao Development Zone, Yuhang, Hangzhou, China

Shanghai Kinding Industrial Co., Ltd: Tel:+86-21-26226658 68938887; Address: No. 347 Yushan Rd., Shanghai, China

Hangzhou Pharma & Chem Co.,Ltd.: Tel:+86-571-87040515; Address: Rm.1201,QinglianBldg.No,139QingchunRd,HangzhouCity,Zhejiang,China

Beijing J&R Times Technology Co., Ltd.: Tel:+86-10-64424939; Address: A1403,Rome garden, No.18, Huixin West Street, Chaoyang District, Beijing, China

Tianjin Weijie Technology Co., Ltd.: Tel:; Address: 5/F,NO.2 Building,NO.236,baidi Road,nankai District,TJ

Zhejiang Chempharm Industry & Trading Co., Ltd.: Tel:0086-571-87701568 87701600; Address: 12,lianhuafeng road,yuhuangshan, Hangzhou,China

Beijing huafeng united technology co.,ltd: Tel:; Address: NO.18 Jianguo RD, Chaoyang district, Beijing, China

Yangzhong Kangda Chemistry Industry Ltd.: Tel:; Address: Steamship Harbor in Bajiao Town in Yangzhong City of Jiangsu Province

FAITH EAGLE (LABORATORY) LTD.: Tel:(+86-755) 82851290; Address: 15A/F.,Block A,World Trade Plaza,8# FuHong Rd., FuTian,Shenzhen, China

SINOCO CHEMICAL CO., LIMITED: Tel:+86-571-81956191, 81956192; Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China.

Qingdao BassTech Co., Ltd.: Tel:; Address: RM 2527, Zhongshang Building, 100 Xianggang Zhong Road, Qingdao, China

AQCHEM, LLC: Tel:+1 925.964.1221; Address: 151 Lindbergh Ave.,Suite E Airport Oaks Business Park Livermore, CA 94551 USA

J.INC.: Tel:+91 79 30903703; Address: 303, 3rd Floor, Royale Manor, Law Garden,Ellisbridge, Ahmedabad - 380006,Gujarat, India

Cangzhou Goldlion Chemicals Co., Ltd.: Tel:+86-(317)-3200188; Address: 402-1, No.5th Building, Chaoyang Huayuan Area ,NO.32, Yuhe Road ,Cangzhou City, Hebei Province, PRC, Cangzhou, Hebei 061001,

Lafutidine cas no:118288-08-7

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