118288-08-7|LafutidineProducts Supply - Chemical intermediates Network

Lafutidine cas no:118288-08-7

Synonyms: Acetamide,2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-,(+)- (9CI);Acetamide,2-[(2-furanylmethyl)sulfinyl]-N-[4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-,(Z)-(+)-;(+)-2-(Furfurylsulfinyl)-N-[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]acetamide;(+)-Lafutidine;FRG 8813;Protecadin;Stogar;

Identification

NameLafutidine
CAS118288-08-7
SynonymsAcetamide,2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-,(+)- (9CI);Acetamide,2-[(2-furanylmethyl)sulfinyl]-N-[4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-,(Z)-(+)-;(+)-2-(Furfurylsulfinyl)-N-[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]acetamide;(+)-Lafutidine;FRG 8813;Protecadin;Stogar;
Molecular FormulaC₂₂H₂₉N₃O₄S
Molecular Weight431.55

Chemical Properties

AppearanceYellowish white crystalline powder
refractive index1.598

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD	oral	> 400mg/kg (400mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 417, 1995.
mouse	LD50	intravenous	47900ug/kg (47.9mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 143, 1995.
mouse	LD50	oral	1034mg/kg (1034mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 143, 1995.
rat	LD50	intravenous	84mg/kg (84mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 143, 1995.
rat	LD50	oral	1248mg/kg (1248mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 143, 1995.

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Tianjin Harmony Technology Development Co., Ltd.: Tel:; Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

Shangyu Zhongchang Chemical Co.,LTD.: Tel:; Address: Shangyu chemical zone,zhejiang,China

Shanghai Jinhong Bio-Pharmaceutical Technology Co...: Tel:+86-21-51996950; Address: Building A, No.688 Qiushi Road, Jinshan district, Shanghai, China

Zhejiang Medicines & Health Products Import & Exp...: Tel:; Address: ZMC Building,101-2 N. Zhongshan Road,Hangzhou,China.

Hangzhou Rongda Pharm & Chem Co, Ltd.: Tel:0571-28889928; Address: Xinqiao Development Zone, Yuhang, Hangzhou, China

Shanghai Kinding Industrial Co., Ltd: Tel:+86-21-26226658 68938887; Address: No. 347 Yushan Rd., Shanghai, China

Hangzhou Pharma & Chem Co.,Ltd.: Tel:+86-571-87040515; Address: Rm.1201,QinglianBldg.No,139QingchunRd,HangzhouCity,Zhejiang,China

Changzhou Xixialong International Trade Co.,ltd.: Tel:; Address: Room 5002, Modern city,Huangshanlu, Xinbei district, Changzhou, China

Chemfar Ltd.: Tel:; Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China

HuaiBei SanHe Developing Co., Ltd.: Tel:86-561-3191113; Address: Room 201,Building ZY-1,GuCheng Road,Huaibei,Anhui,China

Beijing J&R Times Technology Co., Ltd.: Tel:+86-10-64424939; Address: A1403,Rome garden, No.18, Huixin West Street, Chaoyang District, Beijing, China

Beijing Lunarsun Pharmaceutical Co.Ltd.: Tel:086-10-81760039 80771377 80771378 80771379 81760170 81760171 81760172; Address: C1-802, Yangguangguangchang, Anli Road No.68 ,Chaoyang District , 100101 , Beijing , P.R.China

Beijing Mediking Biopharm Co.,Ltd.: Tel:; Address: Hongxianghong Incubator, Beiqijia Town ,Changping district, Beijing, China

Tianjin Weijie Technology Co., Ltd.: Tel:; Address: 5/F,NO.2 Building,NO.236,baidi Road,nankai District,TJ

Zhejiang Chempharm Industry & Trading Co., Ltd.: Tel:0086-571-87701568 87701600; Address: 12,lianhuafeng road,yuhuangshan, Hangzhou,China

Lafutidine cas no:118288-08-7

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