D-Streptamine,O-2,6-diamino-2,6-dideoxy-b-L-idopyranosyl-(1®3)-O-b-D-ribofuranosyl-(1®5)-O-[2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl-(1®4)]-2-deoxy- cas no:119-04-0
Synonyms: 5)]-2-deoxy-;Neomycin B (8CI);Actilin;Actiline;Antibiotic 10676;Antibiotique EF 185;Dekamycin III;Enterfram;Fradiomycin B;Framidal;Framycetin;Framycin;Framygen;Francetin;Fraquinol;Leo Red Dry Cow;
NameD-Streptamine,O-2,6-diamino-2,6-dideoxy-b-L-idopyranosyl-(1®3)-O-b-D-ribofuranosyl-(1®5)-O-[2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl-(1®4)]-2-deoxy-
CAS119-04-0
Synonyms5)]-2-deoxy-;Neomycin B (8CI);Actilin;Actiline;Antibiotic 10676;Antibiotique EF 185;Dekamycin III;Enterfram;Fradiomycin B;Framidal;Framycetin;Framycin;Framygen;Francetin;Fraquinol;Leo Red Dry Cow;
EINECS(EC#)204-292-2
Molecular FormulaC23H46 N6 O13
Molecular Weight614.75
AppearanceClear Liquid
storage temp2-8°C
Hazard Xn: Harmful;
Risk R42/43
Safety
Poison by intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:
Xn
Risk Statements:
R42/43:May cause sensitization by inhalation and skin contact.
R63:Possible risk of harm to the unborn child.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 2
F:
F 8: Photosensitive.
Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
mouse |
LD50 |
intraperitoneal |
250mg/kg (250mg/kg) |
|
"Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 1, Pg. 741, 1978. |
mouse |
LD50 |
intravenous |
24mg/kg (24mg/kg) |
|
Journal of Antibiotics. Vol. 27, Pg. 677, 1974. |
mouse |
LD50 |
oral |
1250mg/kg (1250mg/kg) |
|
"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 1, Pg. 127, 1980. |
mouse |
LD50 |
subcutaneous |
220mg/kg (220mg/kg) |
|
"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 2, Pg. 121, 1957. |