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1H-Imidazole,1-[(2-fluorophenyl)(4-fluorophenyl)phenylmethyl]- cas no:119006-77-8

Synonyms: 1-[(2-Fluorophenyl)-(4-fluorophenyl)phenylmethyl]-1H-imidazole;UR 4056;

Identification
Name1H-Imidazole,1-[(2-fluorophenyl)(4-fluorophenyl)phenylmethyl]-
CAS119006-77-8
Synonyms1-[(2-Fluorophenyl)-(4-fluorophenyl)phenylmethyl]-1H-imidazole;UR 4056;
Molecular FormulaC22H16F2N2
Molecular Weight346.37
Chemical Properties
refractive index1.59
Safety Data

Safety

 Flutrimazole (CAS NO.119006-77-8) may cause burning, irritation, pruritus and erythema in the treated zone. It shows a very low acute toxicity. Its topical administration does not cause sensitization and has no potential for inducing phototoxicity or photosensitivity.


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 2gm/kg (2000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: TREMOR
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 42, Pg. 841, 1992.
mouse LD50 oral > 1gm/kg (1000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: TREMOR
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 42, Pg. 841, 1992.
rat LD50 intraperitoneal 1079mg/kg (1079mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: TREMOR
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 42, Pg. 841, 1992.
rat LD50 oral 808mg/kg (808mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: TREMOR
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 42, Pg. 841, 1992.

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