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tranexamic acid cas no:1197-18-8

Synonyms: trans-4-Aminomethylcyclohexane-1-carboxylate; trans-4-(Aminomethyl)cyclohexanecarboxylic acid; Amstat; amcha; trans-cyclohexanecarboxylic acid

Identification
Nametranexamic acid
CAS1197-18-8
Synonymstrans-4-Aminomethylcyclohexane-1-carboxylate; trans-4-(Aminomethyl)cyclohexanecarboxylic acid; Amstat; amcha; trans-cyclohexanecarboxylic acid
EINECS(EC#)214-818-2
Molecular FormulaC8H15NO2
Molecular Weight157.21
Chemical Properties
Appearancewhite crystalline powder
storage tempStore at 0°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
HazardclassIRRITANT
Safety Data

Hazard Xi:Irritant
Risk R36/37/38
Safety

Moderately toxic by ingestion and intravenous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes such as NOx. A hemostatic agent.
The Hazard Codes of? Tranexamic acid (CAS NO.1197-18-8)? Xi:;
The Risk Statements R36/37/38 : Irritating to eyes, respiratory system and skin.
The Safety Statements?S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.S37/39 : Wear suitable gloves and eye/face protection.


Toxicity
1. ???

orl-mus TDLo:9?mg/kg (female 7-12D post):REP

??? OYYAA2 ?? Oyo Yakuri. Pharmacometrics. 5 (1971),415.
2. ???

orl-rat TDLo:9?mg/kg (female 9-14D post):TER

??? OYYAA2 ?? Oyo Yakuri. Pharmacometrics. 5 (1971),415.
3. ???

orl-rat LD50:3000?mg/kg

??? APTOA6 ?? Acta Pharmacologica et Toxicologica. 22 (1965),340.
4. ???

ipr-rat LD50:4200?mg/kg

??? MEIEDD ?? Merck Index. 10 (1983),1269.
5. ???

scu-rat LD50:4620?mg/kg

??? NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),512.
6. ???

ivn-rat LD50:1200?mg/kg

??? APTOA6 ?? Acta Pharmacologica et Toxicologica. 22 (1965),340.
7. ???

scu-mus LD50:5310?mg/kg

??? NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),512.
8. ???

ivn-mus LD50:1350?mg/kg

??? NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),512.
9. ???

ivn-dog LD50:1110?mg/kg

??? NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),512.

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Zhejiang Medicines and Health Products Import & Export Co., Ltd.
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Hunan Dongting Pharmaceutical Co., Ltd.
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Choriway International Trade Co., Ltd.
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China Changzhou Aitan Chemical Co., Ltd.
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Wuxi Hexia Chemical Company
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Biocon India
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goldhosen
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