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2H-1-Benzopyran-2-one,6,7-dimethoxy- cas no:120-08-1

Synonyms: Coumarin,6,7-dimethoxy- (6CI,7CI,8CI);6,7-Dimethylesculetin;Aesculetin dimethyl ether;Esculetin 6,7-dimethyl ether;Esculetindimethyl ether;NRB 03190;O,O-Dimethylesculetin;O-Methylisoscopoletin;O-Methylscopoletin;Scoparone;Scopoletin methyl ether;Scopoletinmonomethyl ether;

Identification
Name2H-1-Benzopyran-2-one,6,7-dimethoxy-
CAS120-08-1
SynonymsCoumarin,6,7-dimethoxy- (6CI,7CI,8CI);6,7-Dimethylesculetin;Aesculetin dimethyl ether;Esculetin 6,7-dimethyl ether;Esculetindimethyl ether;NRB 03190;O,O-Dimethylesculetin;O-Methylisoscopoletin;O-Methylscopoletin;Scoparone;Scopoletin methyl ether;Scopoletinmonomethyl ether;
EINECS(EC#)204-369-0
Molecular FormulaC11H10O4
Molecular Weight206.21
Chemical Properties
refractive index1.556
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn: Harmful;
Risk R23/24/25
Safety

Hazard Codes HarmfulXn
Risk Statements 23/24/25-36-22 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R36:Irritating to eyes.
R22:Harmful if swallowed.
Safety Statements 27/28-36/37/39-45-26
S27:Take off immediately all contaminated clothing.
S28:After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR 2811
RTECS GN6550000
HazardClass 6.1(b)
PackingGroup III


Toxicity
1.    

orl-rat LD50:292 mg/kg

    DRFUD4    Drugs of the Future. 3 (1978),550.
2.    

ipr-rat LD50:190 mg/kg

    DRFUD4    Drugs of the Future. 3 (1978),550.
3.    

orl-mus LD50:280 mg/kg

    DRFUD4    Drugs of the Future. 3 (1978),550.
4.    

ipr-mus LD50:180 mg/kg

    IJMRAQ    Indian Journal of Medical Research. 60 (1972),763.

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Extrasynthese
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