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Catechol cas no:120-80-9

Synonyms: 1,2-Benzenediol (pyrocatechol); 1,2-benzenediol[qr]; 1,2-dihydroxybenzene[qr]; 2-Hydroxyphenol; 2-hydroxyphenol[qr]; ai3-03995[qr]; Benzene, o-dihydroxy-; benzene,1,2-dihydroxy-; Pyrocatechol

Identification
NameCatechol
CAS120-80-9
Synonyms1,2-Benzenediol (pyrocatechol); 1,2-benzenediol[qr]; 1,2-dihydroxybenzene[qr]; 2-Hydroxyphenol; 2-hydroxyphenol[qr]; ai3-03995[qr]; Benzene, o-dihydroxy-; benzene,1,2-dihydroxy-; Pyrocatechol
EINECS(EC#)204-427-5
Molecular FormulaC6H6O2
Molecular Weight110.11
Chemical Properties
AppearanceLight grey to light brown flake
refractive index1.612
storage tempStore at RT.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard Xn:Harmful
Risk R21/22;R36/38
Safety

Hazard Codes:?HarmfulXn
Risk Statements: 21/22-36/38?
R21/22: Harmful in contact with skin and if swallowed
R36/38: Irritating to eyes and skin
Safety Statements: 22-26-37?
S22: Do not breathe dust
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S37: Wear suitable gloves
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 2
RTECS: UX1050000
HazardClass: 6.1
PackingGroup: III
Poison by ingestion, subcutaneous, intraperitoneal, intravenous, and parenteral routes. Moderately toxic by skin contact. Experimental reproductive effects. Can cause dermatitis on skin contact. An allergen.Questionable carcinogen. Systemic effects similar to those of phenol. Combustible when exposed to heat or flame; can react vigorously with oxidizing materials. Hypergolic reaction with concentrated nitric acid. To fight fire, use water, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 oral 100mg/kg (100mg/kg) ? International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
dog LD50 oral 130mg/kg (130mg/kg) ? International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
dog LDLo intravenous 40mg/kg (40mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 62, 1955.
frog LDLo parenteral 160mg/kg (160mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 166, Pg. 437, 1932.
frog LDLo subcutaneous 160mg/kg (160mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 62, 1955.
guinea pig LD50 oral 210mg/kg (210mg/kg) ? Advances in Food Research. Vol. 3, Pg. 197, 1951.
guinea pig LDLo intraperitoneal 150mg/kg (150mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 62, 1955.
guinea pig LDLo subcutaneous 200mg/kg (200mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 62, 1955.
mammal (species unspecified) LD50 oral 240mg/kg (240mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 15, Pg. 136, 1979.
mouse LD50 intraperitoneal 68mg/kg (68mg/kg) ? Pharmacology and Toxicology Vol. 64, Pg. 247, 1989.
?
mouse LD50 oral 260mg/kg (260mg/kg) ? Advances in Food Research. Vol. 3, Pg. 197, 1951.
mouse LD50 subcutaneous 247mg/kg (247mg/kg) ? Industrial Health. Vol. 5, Pg. 143, 1967.
rabbit LD50 skin 800mg/kg (800mg/kg) SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE American Industrial Hygiene Association Journal. Vol. 37, Pg. 596, 1976.
rabbit LDLo oral 200mg/kg (200mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BLOOD: LEUKOPENIA

BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2A, Pg. 2585, 1981.
rabbit LDLo subcutaneous 225mg/kg (225mg/kg) ? Journal of Agricultural and Food Chemistry. Vol. 17, Pg. 497, 1969.
rat LD50 oral 260mg/kg (260mg/kg) ? Advances in Food Research. Vol. 3, Pg. 197, 1951.
rat LDLo subcutaneous 110mg/kg (110mg/kg) ? Archives Internationales de Pharmacodynamie et de Therapie

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Address: No 9-4 , industrial park,east taihu road, Xinbei

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