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Donepezil cas no:120014-06-4

Synonyms: 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine;Donepezil base;

Identification
NameDonepezil
CAS120014-06-4
Synonyms1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine;Donepezil base;
Molecular FormulaC24H29NO3
Molecular Weight379.49
Chemical Properties
Appearancewhite or almost white crystal powder
refractive index1.578
Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Safety Information of?Donepezil (CAS NO.120014-06-4):
Hazard Codes: Xi
Risk Statements: 36/37/38
36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-36
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
RIDADR: UN 2811


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo oral 1mg/kg (1mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE

GASTROINTESTINAL: NAUSEA OR VOMITING
Annals of Pharmacotherpy. Vol. 33, Pg. 812, 1999.

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