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Gold, [1-(thio-kS)-D-glucopyranosato-kO2]- cas no:12192-57-3

Synonyms: D-Glucose,1-thio-, S-gold deriv. (6CI);Gold, (1-thio-D-glucopyranosato)- (8CI);Gold,(1-thio-D-glucopyranosato-O2,S1)-;D-Glucopyranose, 1-thio-, gold complex;(D-Glucopyranosylthio)gold;Aureotan;Auromyose;Aurothioglucose;Aurumine;Authron;Brenol;Glucose, 1-thio-, gold salt (1:1);Glysanol B;Goldthioglucose;Gold, (D-glucopyranosylthio)-;Oronol;Solganal;Solganal B;

Identification
NameGold, [1-(thio-kS)-D-glucopyranosato-kO2]-
CAS12192-57-3
SynonymsD-Glucose,1-thio-, S-gold deriv. (6CI);Gold, (1-thio-D-glucopyranosato)- (8CI);Gold,(1-thio-D-glucopyranosato-O2,S1)-;D-Glucopyranose, 1-thio-, gold complex;(D-Glucopyranosylthio)gold;Aureotan;Auromyose;Aurothioglucose;Aurumine;Authron;Brenol;Glucose, 1-thio-, gold salt (1:1);Glysanol B;Goldthioglucose;Gold, (D-glucopyranosylthio)-;Oronol;Solganal;Solganal B;
EINECS(EC#)235-365-7
Molecular FormulaC6H11 Au O5 S
Molecular Weight 392.20
Chemical Properties
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn: Harmful;
Risk R42/43
Safety

Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. A deadly human poison by an unspecified route. An experimental poison by intramuscular route. Moderately toxic by subcutaneous and intravenous routes. Human systemic effects: nausea or vomiting, cholestatic jaundice, and eye effects. An experimental teratogen. Other experimental reproductive effects. See also GOLD COMPOUNDS. When heated to decomposition it emits very toxic fumes of SOx
Hazard Codes:
HarmfulXn
Risk Statements:
R42/43:May cause sensitization by inhalation and skin contact.
Safety Statements:
S22:Do not breathe dust. 
S36/37:Wear suitable protective clothing and gloves. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: 2811
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 intravenous 1gm/kg (1000mg/kg)   Poultry Science. Vol. 52, Pg. 926, 1973.
chicken LDLo intramuscular 300mg/kg (300mg/kg) BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES

SPINAL CORD: OTHER DEGENERATIVE CHANGES
Toxicology and Applied Pharmacology. Vol. 35, Pg. 223, 1976.
man LDLo unreported 3mg/kg (3mg/kg)   Sammlung von Vergiftungsfaellen. Vol. 10, Pg. 101A, 1939.
man TDLo intramuscular 3357ug/kg/4W- (3.357mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE Journal of Rheumatology. Vol. 12, Pg. 619, 1985.
man TDLo intramuscular 5500ug/kg/10W (5.5mg/kg) LUNGS, THORAX, OR RESPIRATION: COUGH

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Southern Medical Journal. Vol. 88, Pg. 644, 1995.
mouse LD50 intraperitoneal 2gm/kg (2000mg/kg) LIVER: OTHER CHANGES Proceedings of the Society for Experimental Biology and Medicine. Vol. 70, Pg. 498, 1949.
mouse LDLo subcutaneous 1650mg/kg (1650mg/kg)   Experimental Medicine and Surgery. Vol. 3, Pg. 146, 1945.
women TDLo intramuscular 2600ug/kg/15D (2.6mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

LIVER: OTHER CHANGES
Arthritis and Rheumatism. Vol. 27, Pg. 230, 1984.
women TDLo intramuscular 14402ug/kg/2Y (14.402mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

KIDNEY, URETER, AND BLADDER: PROTEINURIS

KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION
Taisha. Molecular Medicine Vol. 12, Pg. 1435, 1975.
women TDLo parenteral 2700ug/kg/4W- (2.7mg/kg) LIVER: "JAUNDICE, CHOLESTATIC" Journal of Rheumatology. Vol. 11, Pg. 843, 1984.

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Boc Sciences
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CarboMer, Inc.
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