122111-03-9|Gemcitabine hydrochlorideProducts Supply

Gemcitabine hydrochloride cas no:122111-03-9

Synonyms: Gemcitabine HCl;2',2'-Difluorodeoxycytidine monohydrochloride;2'-Deoxy-2',2'-difluorocytidine monohydrochloride;2'-Deoxy-2',2'-difluorocytidine monohydrochloride (beta-isomer);

Identification

NameGemcitabine hydrochloride
CAS122111-03-9
SynonymsGemcitabine HCl;2',2'-Difluorodeoxycytidine monohydrochloride;2'-Deoxy-2',2'-difluorocytidine monohydrochloride;2'-Deoxy-2',2'-difluorocytidine monohydrochloride (beta-isomer);
Molecular FormulaC₉H₁₁F₂N₃O₄^.HCl
Molecular Weight299.66

Chemical Properties

AppearanceWhite crystalline granular, odorless

Safety Data

Hazard Xi: Irritant;
Risk R21
Safety

Hazard Codes:? Harmful Xn,Xi
Risk Statements: 21-36/38-46-62-63
R21: Harmful in contact with skin.
R36/38: Irritating to eyes and skin.?
R46: May cause heritable genetic damage.?
R62: Risk of impaired fertility.?
R63: Possible risk of harm to the unborn child.
Safety Statements: 25-26-36/37-53
S25: Avoid contact with eyes.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37: Wear suitable protective clothing and gloves.?
S53: Avoid exposure - obtain special instructions before use.
Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx, HCl, and F?.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	500mg/kg (500mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 42, Pg. 391, 2000.
rat	LD50	intravenous	236mg/kg (236mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 42, Pg. 391, 2000.
women	TDLo	parenteral	300mg/kg/12W- (300mg/kg)	LUNGS, THORAX, OR RESPIRATION: CONSOLIDATION LUNGS, THORAX, OR RESPIRATION: "FIBROSIS, FOCAL (PNEUMOCONIOSIS)" LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Cancer Vol. 80, Pg. 286, 1997.

supplier list

Shanghai Mingdou Chemical Co.,Ltd: Tel:86-21-52912919; Address: Floor 12th, Zhenyuan Building ,No 2052.North Zhongshan Road, Shanghai,China

Shanghai Kinding Industrial Co., Ltd: Tel:+86-21-26226658 68938887; Address: No. 347 Yushan Rd., Shanghai, China

Beijing huafeng united technology co.,ltd: Tel:; Address: NO.18 Jianguo RD, Chaoyang district, Beijing, China

Lianyungang Jinkang Pharmaceutical Technology Co., Ltd.: Tel:0086-0518-85445517; Address: Jinshan Industrial Park, Ganyu County, Lianyungang, Jiangsu 222115,

BrightGene Bio-Medical Technology Co., Ltd.: Tel:+86-(512)-68086131; Address: No.1326, Binhe Road, Suzhou New district, Suzhou, Jiangsu 215011,

Zhejiang Esun Chemical Co., Ltd.: Tel:86-571-56286531; Address: Sandun, Xihu Industry Park, Hangzhou City, Zhejiang 310030,

Apex Drugs & Intermediates Ltd.: Tel:+91-(40)-23706034; Address: 210, Ram's Enclave, Erragadda, Hyderabad, Andhra Pradesh 500018,

Vinkem Labs Private Limited: Tel:+91-(44)-26201796; Address: AH - 29, Shanthi Colony, Anna Nagar, Chennai, Tamil Nadu 600 040,

Shanghai Twisun Bio-pharm Co.,Ltd.: Tel:+86-(21)-37285116; Address: 221,Building F,No.688 Qiushi Road, Jinshan District, Shanghai 201512,

Wuhan Borui Fine Chemical Co., Ltd.: Tel:+86-(27)-8355-0361; Address: No.448 Jinghan Road, QiaoKou, Wuhan, Hubei 430022,

Lianyungang Wanke Bioengineering Co., Ltd.: Tel:+86-(518)-8629-5900; Address: Economic Technical Development Area, Ganyu, Lianyungang, Jiangsu,

Chengdu Zhenhao Tech Co., Ltd.: Tel:; Address:

Jinan ChuanCheng Pharmaceutical R&D Co.,Ltd.: Tel:+86-(531)-88902485; Address: 556 Hualong Road, Jinan, Shandong 250100,

Nanjing Samwon International Limited: Tel:+86-(25)-84873444; Address: 1108, BLDG B, New Century Plaza, No 1, South Taiping Rd., Nanjing, Jiangsu 210002,

Kouting Chemical Co.,Ltd: Tel:+86-(21)-58116473; Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318,

Gemcitabine hydrochloride cas no:122111-03-9

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