122111-03-9|Gemcitabine hydrochlorideProducts Supply

Gemcitabine hydrochloride cas no:122111-03-9

Synonyms: Gemcitabine HCl;2',2'-Difluorodeoxycytidine monohydrochloride;2'-Deoxy-2',2'-difluorocytidine monohydrochloride;2'-Deoxy-2',2'-difluorocytidine monohydrochloride (beta-isomer);

Identification

NameGemcitabine hydrochloride
CAS122111-03-9
SynonymsGemcitabine HCl;2',2'-Difluorodeoxycytidine monohydrochloride;2'-Deoxy-2',2'-difluorocytidine monohydrochloride;2'-Deoxy-2',2'-difluorocytidine monohydrochloride (beta-isomer);
Molecular FormulaC₉H₁₁F₂N₃O₄^.HCl
Molecular Weight299.66

Chemical Properties

AppearanceWhite crystalline granular, odorless

Safety Data

Hazard Xi: Irritant;
Risk R21
Safety

Hazard Codes:? Harmful Xn,Xi
Risk Statements: 21-36/38-46-62-63
R21: Harmful in contact with skin.
R36/38: Irritating to eyes and skin.?
R46: May cause heritable genetic damage.?
R62: Risk of impaired fertility.?
R63: Possible risk of harm to the unborn child.
Safety Statements: 25-26-36/37-53
S25: Avoid contact with eyes.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37: Wear suitable protective clothing and gloves.?
S53: Avoid exposure - obtain special instructions before use.
Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx, HCl, and F?.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	500mg/kg (500mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 42, Pg. 391, 2000.
rat	LD50	intravenous	236mg/kg (236mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 42, Pg. 391, 2000.
women	TDLo	parenteral	300mg/kg/12W- (300mg/kg)	LUNGS, THORAX, OR RESPIRATION: CONSOLIDATION LUNGS, THORAX, OR RESPIRATION: "FIBROSIS, FOCAL (PNEUMOCONIOSIS)" LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Cancer Vol. 80, Pg. 286, 1997.

supplier list

Shanghai Mingdou Chemical Co.,Ltd: Tel:86-21-52912919; Address: Floor 12th, Zhenyuan Building ,No 2052.North Zhongshan Road, Shanghai,China

Dalian Wista Pharmaceutical Co., Ltd: Tel:; Address: No.16, Baimiao Industrial Park, Beiqijia Town, Changping District,102209, Beijing, P. R. China

S.S.T. Corporation: Tel:+1-(973)-473-4300; Address: 635 Brighton Road, Clifton, New Jersey 07012,

Shanghai ZhongYiTai International Trading Co., Ltd.: Tel:; Address:

R & S Pharmachem: Tel:+86-(571)-85774090; Address: 403 B. C. No. 308, North Zhongshan Road, Hangzhou, Zhejiang 310003,

Waycome Pharmaceutical Co., Ltd: Tel:+86-(23)-74578888; Address: 138 YuWu Road, XinMin Town, chonqing 408302,

Jiangsu Yew Pharmaceutical Co., Ltd.: Tel:+86-(510)-6686-5972; Address: Hongdou Industrial District, Donggang Town, Xishan, Wuxi, Jiangsu 214199,

Coben Pharmaceutical Co., Ltd.: Tel:+86-(571)-28021577; Address: B-17/F of Haihua Plaza , No.658 North Jianguo Road, Hangzhou, Zhejiang 310004,

Originchem Co., Ltd.: Tel:+86-(523)-8620-0346; Address: 3rd Floor, G09 Building, China Medical, TaiZhou 225300,

Shanghai Amadis Bio-Technology Co., Ltd: Tel:0086-21-3616 2072, 6117 5616; Address: Suite 2, No.868 Zhenchen Road, Baoshan District, Shanghai, 200 444, China.

Wuhan Senwayer Century chemical Co.,Ltd: Tel:86-27-59009407; Address: 20#Xudong Street,Wuhan China

Jiaxing Isen Chemical Co.,Ltd: Tel:86-573-85280080; Address: Address: Room 301, Unit 2, Building 3, Alley 94, East Renmin Road, Pinghu City, Zhejiang Province, China

Hangzhou Dayangchem Co., Ltd.: Tel:86-571-88938639; Address: 9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road

Hangzhou J&H Chemical Co., Ltd: Tel:86-571-87396430; Address: No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

Finetech Industry limited.: Tel:86-27-87465837; Address: chukang Road, Wuhan, Hubei 430073,

Gemcitabine hydrochloride cas no:122111-03-9

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