Welcome to hiintermediates.com,intermediates trading platform
Home > products > Sodium Aurothiomalate

Sodium Aurothiomalate cas no:12244-57-4

Synonyms: sodium aurothiomalate hydrate; disodium 2-(auriothio)succinate; Gold sodium Thiomalate

Identification
NameSodium Aurothiomalate
CAS12244-57-4
Synonymssodium aurothiomalate hydrate; disodium 2-(auriothio)succinate; Gold sodium Thiomalate
EINECS(EC#)235-479-7
Molecular FormulaC4H3AuNa2O4S
Molecular Weight390.07
Safety Data

Hazard Xn:Harmful;
Risk R20/21/22;R43
Safety

Poison by subcutaneous and intramuscular routes. Moderately toxic by intravenous route. Human systemic effects: aggression, agranulocytosis, aplastic anemia, cell count changes, changes in circulation, cholestatic jaundice, dermatitis, encephalitis, fasciculations, flaccid paralysis without anesthesia, hemorrhage, hepatitis (hepatocellular necrosis), increased body temperature, interstitial fibrosis, muscle weakness, proteinuria, recording from peripheral motor nerve, depressed renal function tests, somnolence, structural changes in nerve sheath, thrombocytopenia, uncharacterized allergic reaction, changes in blood, teeth, and supporting structures. Experimental teratogenic and reproductive effects. When heated to decomposition it emits very toxic Na2O and SOx.
Safety Information about Disodium; gold(1+); 2-sulfidobutanedioate (CAS NO.12244-57-4):
Hazard Codes: 
Xn:
Risk Statements about Disodium; gold(1+); 2-sulfidobutanedioate (CAS NO.12244-57-4):
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R43: May cause sensitization by skin contact.
Safety Statements about Disodium; gold(1+); 2-sulfidobutanedioate (CAS NO.12244-57-4): 
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: MD5435000


Toxicity
1.    

orl-man TDLo:5500 µg/kg:PNS,KID,BLD

    ARHEAW    Arthritis and Rheumatism. 19 (1976),936.
2.    

ims-wmn TDLo:182 µg/kg:SKN

    BMJOAE    British Medical Journal. 2 (1976),1294.
3.    

ivn-wmn TDLo:2700 µg/kg/4W-I:CNS

    JRHUA9    Journal of Rheumatology. 11 (1984),235.
4.    

ims-wmn TDLo:20 mg/kg/1Y:CNS,KID

    ARPAAQ    Archives of Pathology. 96 (1973),133.
5.    

ims-man TDLo:5 mg/kg/13W:BLD,MSK

    JAMAAP    JAMA, Journal of the American Medical Association. 133 (1947),754.
6.    

ims-wmn LDLo:600 µg/kg/1W-I:PUL,SYS

    JRSMD9    Journal of the Royal Society of Medicine. 77 (1984),960.
7.    

par-wmn TDLo:3366 µg/kg/2W:CNS,PNS

    NEURAI    Neurology. 20 (1970),455.
8.    

par-man TDLo:12,500 µg/kg/7W-I:CNS,PNS

    JRHUA9    Journal of Rheumatology. 11 (1984),233.
9.    

par-man TDLo:7857 µg/kg/11W-I:SKN

    BMJOAE    British Medical Journal. 286 (1983),1547.
10.    

unr-cld TDLo:11,900 µg/kg/18W-I:

    JRHUA9    Journal of Rheumatology. 13 (1986),224.
 

supplier list

Colonial Metals, Inc.
Tel:+1-(410)-398-7200
Address: Triumph Ind Complex, PO 726, Elkton, Maryland 21921,
DF Goldsmith Chemical & Metal Corp
Tel:
Address:
Synthon Chemicals
Tel:+27-21-975 3401
Address: Reg No. 84/107096/07 P.O. Box 647, Stellenbosch, 7599, South Africa.
Almat Pharmachem Inc.
Tel:
Address:
Boc Sciences
Tel:1-631-5046093
Address: 45-16 Ramsey Road Shirley, NY 11967, USA
AFINE CHEMICALS LIMITED
Tel:86-571-85232161
Address: 6th Floor, Block C, 7th Building, Xigang Xinjie, Xihu Industrial Park, Sandun Town, Hangzhou, China

Home   |   About Us   |   Service   |   Links   |   Add to  Favorite

Copyright©2011 HiIntermediates ICP: B2-20090288 浙ICP备09045134号-49
Tel: +86-0571-89739792