5H-Dibenzo[a,d]cycloheptene-5-propanamine,N-methyl-, hydrochloride (1:1) cas no:1225-55-4

Name5H-Dibenzo[a,d]cycloheptene-5-propanamine,N-methyl-, hydrochloride (1:1)
CAS1225-55-4
Synonyms5H-Dibenzo[a,d]cycloheptene-5-propanamine,N-methyl-, hydrochloride (9CI); 5H-Dibenzo[a,d]cycloheptene-5-propylamine,N-methyl-, hydrochloride (7CI,8CI); Concordin; MK-240; Maximed; Maximet;N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propylamine hydrochloride; NormethylEX4442; Protriptyline hydrochloride; Protryptyline hydrochloride; Triptil;Triptil Hydrochloride; Vivactil
EINECS(EC#)214-956-3
Molecular FormulaC19H21 N . Cl H
Molecular Weight299.87

Hazardclass6.1(b)

Hazard Xn: Harmful;
Risk 20/21/22-36/37/38
Safety

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NO_x and HCl.
Hazard Codes of Protriptyline hydrochloride (CAS NO.1225-55-4): Xn
Risk Statements: 20/21/22-36/37/38 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.

1.		orl-rat LD50:299 mg/kg		TXAPA9    Toxicology and Applied Pharmacology. 18 (1971),185.
2.		ipr-rat LD50:44 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,88.
3.		orl-mus LD50:211 mg/kg		TXAPA9    Toxicology and Applied Pharmacology. 18 (1971),185.
4.		scu-mus LD50:192 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,88.
5.		ivn-mus LD50:49 mg/kg		APTOA6    Acta Pharmacologica et Toxicologica. 24 (1966),121.
6.		orl-dog LDLo:400 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,88.
7.		orl-rbt LD50:310 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,88.
8.		ivn-rbt LD50:8200 µg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,88.
9.		orl-gpg LD50:180 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,88.
10.