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Crotonaldehyde cas no:123-73-9

Synonyms: (E)-2-Butenal; (E)-Crotonaldehyde; trans-2-Butenal; trans-crotonaldehyde; ; Crotonaldehyde; trans-But-2-enal; β-Methyl acrolein

Identification
NameCrotonaldehyde
CAS123-73-9
Synonyms(E)-2-Butenal; (E)-Crotonaldehyde; trans-2-Butenal; trans-crotonaldehyde; ; Crotonaldehyde; trans-But-2-enal; β-Methyl acrolein
EINECS(EC#)204-647-1
Molecular FormulaC4H6O
Molecular Weight70.09
Chemical Properties
AppearanceWater-white, mobile liquid. Pungent, suffocating odor.
refractive index1.4355-1.4375
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard F:Flammable;T+:Verytoxic;N:Dangerousfortheenvironment;
Risk R11;R24/25;R26;R37/38;R41;R48/22;R50;R68
Safety

Hazard Codes: FlammableF,VeryT+,DangerousN
Risk Statements: 11-23/25-26-37/38-41-48/22-50-68 
R11: Highly flammable. 
R23/25: Toxic by inhalation and if swallowed. 
R37/38: Irritating to respiratory system and skin. 
R41: Risk of serious damage to the eyes. 
R48/22: Harmful: danger of serious damage to health by prolonged exposure if swallowed. 
R50: Very toxic to aquatic organisms. R68:Possible risk of irreversible effects.
Safety Statements: 26-28-36/37/39-45-61-28A 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S28: After contact with skin, wash immediately with plenty of soap-suds. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 1143 6.1/PG 1
WGK Germany: 3
RTECS: GP9625000
F: 9-13-23
HazardClass: 6.1
PackingGroup: I


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo subcutaneous 568mg/kg (568mg/kg)   Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 18, Pg. 218, 1884.
guinea pig LDLo subcutaneous 1331mg/kg (1331mg/kg)   Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 18, Pg. 218, 1884.
human TCLo inhalation 12mg/m3/10M (12mg/m3) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
JAMA, Journal of the American Medical Association. Vol. 165, Pg. 1908, 1957.
 
mouse LC50 inhalation 1510mg/m3/2H (1510mg/m3) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: ATAXIA

BEHAVIORAL: EXCITEMENT
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 6(9), Pg. 34, 1962.
mouse LD50 intraperitoneal 160mg/kg (160mg/kg)   Personal Communication from H. Zollner, Institut fur Biochemie, Der Universitat, Gras, Oct. 23, 1975Vol. 23OCT1975,
mouse LD50 oral 240mg/kg (240mg/kg)   Biochemical Journal. Vol. 34, Pg. 1196, 1940.
mouse LD50 subcutaneous 160mg/kg (160mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.
rabbit LD50 skin 380mg/kg (380mg/kg)   Union Carbide Data Sheet. Vol. 4/21/1967,
rat LC50 inhalation 4000mg/m3/30M (4000mg/m3) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.
rat LD50 subcutaneous 140mg/kg (140mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.

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