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Clofarabine cas no:123318-82-1

Synonyms: C1-F-Ara-A;9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-;2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine;Clofarabine, 5-(6-Amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;5-(6-Amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;Clofarex;Clolar;2-Chloro-9-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-9H-purin-6-amine;(2R,3R,4S,5R)-5-(6-amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;CAFDA;9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-;Clofarabine(Clofarabine or called Keluola foreshore);2-Chloro-6-amino-purine-2'-fluoro-2'- deoxy arabineoside;

Identification
NameClofarabine
CAS123318-82-1
SynonymsC1-F-Ara-A;9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-;2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine;Clofarabine, 5-(6-Amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;5-(6-Amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;Clofarex;Clolar;2-Chloro-9-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-9H-purin-6-amine;(2R,3R,4S,5R)-5-(6-amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;CAFDA;9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-;Clofarabine(Clofarabine or called Keluola foreshore);2-Chloro-6-amino-purine-2'-fluoro-2'- deoxy arabineoside;
Molecular FormulaC10H11ClFN5O3
Molecular Weight303.68
Chemical Properties
AppearanceWhite Solid
refractive index1.843
Safety Data

Safety Mutation data reported. When heated to decomposition it emits toxic vapors of NOx, F?, and Cl?.

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UD7473000
CHEMICAL NAME :
9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) -
CAS REGISTRY NUMBER :
123318-82-1
LAST UPDATED :
199706
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H11-Cl-F-N5-O3
MOLECULAR WEIGHT :
303.71

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Human Leukocyte
DOSE/DURATION :
50 nmol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 51,2386,1991

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