123318-82-1|ClofarabineProducts Supply - Chemical intermediates Network

Clofarabine cas no:123318-82-1

Synonyms: C1-F-Ara-A;9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-;2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine;Clofarabine, 5-(6-Amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;5-(6-Amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;Clofarex;Clolar;2-Chloro-9-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-9H-purin-6-amine;(2R,3R,4S,5R)-5-(6-amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;CAFDA;9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-;Clofarabine(Clofarabine or called Keluola foreshore);2-Chloro-6-amino-purine-2'-fluoro-2'- deoxy arabineoside;

Identification

NameClofarabine
CAS123318-82-1
SynonymsC1-F-Ara-A;9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-;2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine;Clofarabine, 5-(6-Amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;5-(6-Amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;Clofarex;Clolar;2-Chloro-9-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-9H-purin-6-amine;(2R,3R,4S,5R)-5-(6-amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;CAFDA;9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-;Clofarabine(Clofarabine or called Keluola foreshore);2-Chloro-6-amino-purine-2'-fluoro-2'- deoxy arabineoside;
Molecular FormulaC₁₀H₁₁ClFN₅O₃
Molecular Weight303.68

Chemical Properties

AppearanceWhite Solid
refractive index1.843

Safety Data

Safety Mutation data reported. When heated to decomposition it emits toxic vapors of NOx, F?, and Cl?.

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UD7473000

CHEMICAL NAME :: 9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) -

CAS REGISTRY NUMBER :: 123318-82-1

LAST UPDATED :: 199706

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H11-Cl-F-N5-O3

MOLECULAR WEIGHT :: 303.71

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Leukocyte

DOSE/DURATION :: 50 nmol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 51,2386,1991

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