124750-99-8|Losartan potassiumProducts Supply - Chemical intermediates Network

Losartan potassium cas no:124750-99-8

Synonyms: Lotim;L-158086;Ocsaar;Losacor;Tenopres;Lortaan;Losaprex;Hyzaar;Niten;DuP 753;Losartan monopotassium salt;MK 954;Lorzaan;Cozaar;Llosartan;Losartanpotassium;Lorzaar;1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt;2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium;MK-0954;Losacar;MK 0954;potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;Cozaar (TN);

Identification

NameLosartan potassium
CAS124750-99-8
SynonymsLotim;L-158086;Ocsaar;Losacor;Tenopres;Lortaan;Losaprex;Hyzaar;Niten;DuP 753;Losartan monopotassium salt;MK 954;Lorzaan;Cozaar;Llosartan;Losartanpotassium;Lorzaar;1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt;2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium;MK-0954;Losacar;MK 0954;potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;Cozaar (TN);
Molecular FormulaC₂₂H₂₂ClKN₆OK
Molecular Weight461.01

Chemical Properties

Appearancewhite to off-white crystalline powder

Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Hazard Codes:? Irritant Xi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RTECS: NI6755100

Toxicity

dog	LD	oral	> 320mg/kg (320mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
man	TDLo	oral	10mg/kg/2W-I (10mg/kg)	BLOOD: HEMORRHAGE SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Archives of Internal Medicine. Vol. 158, Pg. 191, 1998.
mouse	LDLo	intraperitoneal	400mg/kg (400mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
mouse	LDLo	oral	1gm/kg (1000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
rat	LDLo	intraperitoneal	200mg/kg (200mg/kg)	BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
rat	LDLo	oral	2gm/kg (2000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
women	TDLo	oral	1mg/kg/1D-I (1mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"	Archives of Internal Medicine. Vol. 158, Pg. 2063, 1998.

supplier list

Dishman Pharmaceuticals and Chemicals Ltd: Tel:+91(79) 26443053; Address: Bhadr-Raj Chambers C.G. Road Navrangpura Ahmedabad - 380 009 Gujarat, INDIA

Chuming Pharmaceutical Limited: Tel:; Address: 9th Fl.,Garden Building, Jiuzhou Ave. No.1083, Zhuhai,China

SINOCHEM NINGBO LTD.: Tel:86-574-87260209 87348868; Address: 21 Jiangxia St.,Ningbo 315000 .Zhejiang. China

Zhejiang Yulong Chemical Co.,Ltd.: Tel:; Address: NO.165 ZHONGHE ZHONG ROAD, HANGZHOU, CHINA.

Benzo Chemical Industries: Tel:+91-22-2524-3678 / 5575 1356 / 2528 5563.; Address: Vishwam, 8/B Postal Colony, Chembur, Mumbai-400071 India.

HANGZHOU THINK CHEMICAL CO., LTD.: Tel:; Address: ROOM 719 BUILDING D MEIDU PLAZA 789 MOGANSHAN ROAD HANGZHOU CHINA

Taizhou Overseas Int'l Ltd.: Tel:+86-576-8881 2802; Address: 126-8 QINGNIAN ROAD JIAOJIANG TAIZHOU ZHEJIANG CHINA

Nanjing Qida International Trading Co., Ltd: Tel:+86-(25)-8646-0031; Address: B-15A01, 130 Olympic Av., Nanjing, Jiangsu 210019,

Huaian Synniken Chemical Co.,Ltd.: Tel:+86-(10)-87727796; Address: RM.1501, A-101-2, No.1, Baiziwan Road, Chaoyang District, Beijing,

Yibin Wish Pharmaceutical Co., Ltd.: Tel:+86-(831)-5109851, 5109836; Address: Luolong Industrial Zone, Nanxi, Yibin, Sichuan 644104,

Smaart Pharmaceutticals: Tel:+91-(257)-3296354; Address: B-23, Midc, Ajantha Road, Jalgaon, Maharashtra 425003,

Tyche Industries Limited: Tel:+91-(40)-23541688, 23540733; Address: C21/A, Road No-9, Film Nagar, Jubilee Hills, Hyderabad, Andhra Pradesh 500033,

Sibram Pharmaceuticals: Tel:+91-(22)-67997876; Address: E-305, 3rd Floor Kailas Industrial Complex, Park Site, Vikhroli (West), Mumbai, Maharashtra 400079,

Beijing SHLHT Science & Trade Co., Ltd.: Tel:+86-(10)-6883-5641, 6883-5642, 8870-7647; Address: No.5-6-402 Yangzhuangzhongqu Shijingshan District, Beijing 100043,

Edengene Chemical Limited: Tel:+86-(519)-85208709; Address: 1402, Aite Building, 238-2, Tongjiang Nan Road, Changzhou, Jiangsu,

Losartan potassium cas no:124750-99-8

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