124750-99-8|Losartan potassiumProducts Supply - Chemical intermediates Network

Losartan potassium cas no:124750-99-8

Synonyms: Lotim;L-158086;Ocsaar;Losacor;Tenopres;Lortaan;Losaprex;Hyzaar;Niten;DuP 753;Losartan monopotassium salt;MK 954;Lorzaan;Cozaar;Llosartan;Losartanpotassium;Lorzaar;1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt;2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium;MK-0954;Losacar;MK 0954;potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;Cozaar (TN);

Identification

NameLosartan potassium
CAS124750-99-8
SynonymsLotim;L-158086;Ocsaar;Losacor;Tenopres;Lortaan;Losaprex;Hyzaar;Niten;DuP 753;Losartan monopotassium salt;MK 954;Lorzaan;Cozaar;Llosartan;Losartanpotassium;Lorzaar;1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt;2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium;MK-0954;Losacar;MK 0954;potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;Cozaar (TN);
Molecular FormulaC₂₂H₂₂ClKN₆OK
Molecular Weight461.01

Chemical Properties

Appearancewhite to off-white crystalline powder

Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Hazard Codes:? Irritant Xi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RTECS: NI6755100

Toxicity

dog	LD	oral	> 320mg/kg (320mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
man	TDLo	oral	10mg/kg/2W-I (10mg/kg)	BLOOD: HEMORRHAGE SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Archives of Internal Medicine. Vol. 158, Pg. 191, 1998.
mouse	LDLo	intraperitoneal	400mg/kg (400mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
mouse	LDLo	oral	1gm/kg (1000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
rat	LDLo	intraperitoneal	200mg/kg (200mg/kg)	BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
rat	LDLo	oral	2gm/kg (2000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
women	TDLo	oral	1mg/kg/1D-I (1mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"	Archives of Internal Medicine. Vol. 158, Pg. 2063, 1998.

supplier list

Daebong Incheon factory: Tel:+82-32-817-8800; Address: 692-8, Kojan-dong, Namdong-ku, Incheon, KOREA

Beijing Mediking Biopharm Co.,Ltd.: Tel:; Address: Hongxianghong Incubator, Beiqijia Town ,Changping district, Beijing, China

Taizhou Crene Chempharm Co., Ltd.: Tel:+86-(576)-88813233; Address: Weiwu Load Economic Developed Zone, Taizhou, Zhejiang 318000,

Ions Pharma: Tel:+91-(22)-25006213; Address: A-106/107. Kanara Business Centre (KBC), Near Laxmi Nagar. Ghatkopar (E), Mumbai, Maharashtra 400086,

Dalian Huitong International Co., Ltd: Tel:+86-0411-39756198,39792808,84800785; Address: Rm1201,Xinghaiwangzuo Building,no.572 Zhongshan road,Dalian,China

shanghai sphchem co.,ltd: Tel:+86-21-56491756 13512199871; Address: NO.133, Wuye, Yangxin Road ,Shanghai China

SynFine Research, Inc.: Tel:+1-(905)-737-2702; Address: 120 Newkirk Road Unit 19, Richmond Hill, Ontario L4C 9S7,

Nanjing Bangnuo Biotechnology Co., Ltd: Tel:86-1732-7098554; Address: shuanglong road,jiangning, nanjing,jiangsu

Nanjing Bangnuo Biotechnology Co., Ltd: Tel:86-1732-7098554; Address: shuanglong road,jiangning, nanjing,jiangsu

Nanjing Bangnuo Biotechnology Co., Ltd: Tel:86-1732-7098554; Address: shuanglong road,jiangning, nanjing,jiangsu

Nanjing Bangnuo Biotechnology Co., Ltd: Tel:86-1732-7098554; Address: shuanglong road,jiangning, nanjing,jiangsu

shijiazhuang guizheng trade co.,ltd: Tel:86-312-18103315327; Address: east huaxia road pudong shanghai china

Nanjing Bangnuo Biotechnology Co., Ltd.: Tel:86-25-52113793; Address: Room 901 Tianqinwan Garden NO.1008 Ssangyong Avenu

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Losartan potassium cas no:124750-99-8

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