124750-99-8|Losartan potassiumProducts Supply - Chemical intermediates Network

Losartan potassium cas no:124750-99-8

Synonyms: Lotim;L-158086;Ocsaar;Losacor;Tenopres;Lortaan;Losaprex;Hyzaar;Niten;DuP 753;Losartan monopotassium salt;MK 954;Lorzaan;Cozaar;Llosartan;Losartanpotassium;Lorzaar;1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt;2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium;MK-0954;Losacar;MK 0954;potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;Cozaar (TN);

Identification

NameLosartan potassium
CAS124750-99-8
SynonymsLotim;L-158086;Ocsaar;Losacor;Tenopres;Lortaan;Losaprex;Hyzaar;Niten;DuP 753;Losartan monopotassium salt;MK 954;Lorzaan;Cozaar;Llosartan;Losartanpotassium;Lorzaar;1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt;2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium;MK-0954;Losacar;MK 0954;potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;Cozaar (TN);
Molecular FormulaC₂₂H₂₂ClKN₆OK
Molecular Weight461.01

Chemical Properties

Appearancewhite to off-white crystalline powder

Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Hazard Codes:? Irritant Xi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RTECS: NI6755100

Toxicity

dog	LD	oral	> 320mg/kg (320mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
man	TDLo	oral	10mg/kg/2W-I (10mg/kg)	BLOOD: HEMORRHAGE SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Archives of Internal Medicine. Vol. 158, Pg. 191, 1998.
mouse	LDLo	intraperitoneal	400mg/kg (400mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
mouse	LDLo	oral	1gm/kg (1000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
rat	LDLo	intraperitoneal	200mg/kg (200mg/kg)	BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
rat	LDLo	oral	2gm/kg (2000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
women	TDLo	oral	1mg/kg/1D-I (1mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"	Archives of Internal Medicine. Vol. 158, Pg. 2063, 1998.

supplier list

Dishman Pharmaceuticals and Chemicals Ltd: Tel:+91(79) 26443053; Address: Bhadr-Raj Chambers C.G. Road Navrangpura Ahmedabad - 380 009 Gujarat, INDIA

Sunasia Co., Ltd.: Tel:; Address: Suite 1503, 15Fl., Huijin Mansion, No. 77 He Yi Road, Ningbo 315000 China

CIDIC Co.,Ltd.: Tel:; Address: 15/F, HODO International Plaza, 531 Zhongshan Road, Wuxi, China

Chemfar Ltd.: Tel:; Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China

VASUDHA PHARMA CHEM LIMITED: Tel:+91-40-23812046, 23814987, 23711715, 23711717; Address: 78/A, Vengalrao nagar,Hyderabad - 500 038.Andhra Pradesh, INDIA.

Benzo Chemical Industries: Tel:+91-22-2524-3678 / 5575 1356 / 2528 5563.; Address: Vishwam, 8/B Postal Colony, Chembur, Mumbai-400071 India.

HANGZHOU THINK CHEMICAL CO., LTD.: Tel:; Address: ROOM 719 BUILDING D MEIDU PLAZA 789 MOGANSHAN ROAD HANGZHOU CHINA

MAPRIMED S.A.: Tel:(54-11) 4630-1500 / 1512; Address: Dr. Jorge Gallo Pecca Av. Gral. E. Garz贸n 5928 C1440AYV Buenos Aires, Argentina

Huaibei Sanhe Additive Co., Ltd: Tel:; Address: NO.220 Gucheng Road,Huaibei,Anhui,China

Ningbo Victory & Prosperity Chemistry CO.,LTD.: Tel:+86-(574)-27666767; Address: 21/F, No.11 Bldg, Xin Tian Di, NO 689, Shi Ji Road, NINGBO 315040,

Zhejiang Jiangbei Pharmaceutical Co., Ltd.: Tel:+86-(576)-8786668; Address: Dongdai Zhangan Street, Jiaojiang, Taizhou, Zhejiang 318017,

Leawell International Limited: Tel:+852-(2576)-0298; Address: 18/F Catic Plaza, 8 Causeway Road Causeway Bay,

Hetero Drugs Ltd.,: Tel:+91-(40)-23704923; Address: H.No. 8-3-166/7/1, Erragadda, Hyderabad, Andhra Pradesh 500 018,

Shanghai Coming Hi-Technology Co., Ltd.: Tel:+86-(21)-54821359; Address: 4th Floor, Building B. No.18, 1305 Huajing Road, Shanghai 200231,

Yibin Wish Pharmaceutical Co., Ltd.: Tel:+86-(831)-5109851, 5109836; Address: Luolong Industrial Zone, Nanxi, Yibin, Sichuan 644104,

Losartan potassium cas no:124750-99-8

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