124750-99-8|Losartan potassiumProducts Supply - Chemical intermediates Network

Losartan potassium cas no:124750-99-8

Synonyms: Lotim;L-158086;Ocsaar;Losacor;Tenopres;Lortaan;Losaprex;Hyzaar;Niten;DuP 753;Losartan monopotassium salt;MK 954;Lorzaan;Cozaar;Llosartan;Losartanpotassium;Lorzaar;1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt;2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium;MK-0954;Losacar;MK 0954;potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;Cozaar (TN);

Identification

NameLosartan potassium
CAS124750-99-8
SynonymsLotim;L-158086;Ocsaar;Losacor;Tenopres;Lortaan;Losaprex;Hyzaar;Niten;DuP 753;Losartan monopotassium salt;MK 954;Lorzaan;Cozaar;Llosartan;Losartanpotassium;Lorzaar;1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt;2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium;MK-0954;Losacar;MK 0954;potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;Cozaar (TN);
Molecular FormulaC₂₂H₂₂ClKN₆OK
Molecular Weight461.01

Chemical Properties

Appearancewhite to off-white crystalline powder

Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Hazard Codes:? Irritant Xi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RTECS: NI6755100

Toxicity

dog	LD	oral	> 320mg/kg (320mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
man	TDLo	oral	10mg/kg/2W-I (10mg/kg)	BLOOD: HEMORRHAGE SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Archives of Internal Medicine. Vol. 158, Pg. 191, 1998.
mouse	LDLo	intraperitoneal	400mg/kg (400mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
mouse	LDLo	oral	1gm/kg (1000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
rat	LDLo	intraperitoneal	200mg/kg (200mg/kg)	BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
rat	LDLo	oral	2gm/kg (2000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
women	TDLo	oral	1mg/kg/1D-I (1mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"	Archives of Internal Medicine. Vol. 158, Pg. 2063, 1998.

supplier list

Dishman Pharmaceuticals and Chemicals Ltd: Tel:+91(79) 26443053; Address: Bhadr-Raj Chambers C.G. Road Navrangpura Ahmedabad - 380 009 Gujarat, INDIA

Chuming Pharmaceutical Limited: Tel:; Address: 9th Fl.,Garden Building, Jiuzhou Ave. No.1083, Zhuhai,China

SUNWELL CHEMICALS CO.,LTD.(INTERPHARMA TRADING CO...: Tel:; Address: SUITE 1108,GOLDEN PLAZA,NO.118,QING CHUN ROAD,HANGZHOU,ZHEJIANG,CHINA

Luna Chemicals Co.,Ltd.: Tel:; Address: 1502-1503,No.310 North Zhong Shan Rd., Hangzhou,China

Taizhou Zhongrong Chemical Co., Ltd.: Tel:86-576-88603100; Address: 7F, No.71,Huiyan Lu,Jiaojiang Zone,Taizhou City,Zhejiang

ZHEJIANG HOLYPHARM BIOTECH CO.,LTD: Tel:86-533-8585678; Address: Room C 13th Floor, West Wing International Garden, No.160 Tianmushan Road, Xihu District, Hangzhou City, China

Zhejiang Yulong Chemical Co.,Ltd.: Tel:; Address: NO.165 ZHONGHE ZHONG ROAD, HANGZHOU, CHINA.

Dishman USA, Inc.: Tel:732-560-4300 (main) / 978-536-0007 (direct); Address: 550 Union Avenue, Suite 9, Middlesex, NJ 08846

Jiacheng Chem Enterprises: Tel:; Address: 20A Zhejiang material industry building 445 Kaixuan Raod, Hangzhou China

Aliapharm: Tel:+49 69 971412-0; Address: AliaPharm GmbH Frankfurt Niedenau 49 60325 Frankfurt / Main

Chemfar Ltd.: Tel:; Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China

Zhejiang Shaxing Pharma & Chemical Co. Ltd.: Tel:; Address: Yongquan Town Industrial Park, Linhai city, Zhejiang prov., China.

Beijing Mediking Biopharm Co.,Ltd.: Tel:; Address: Hongxianghong Incubator, Beiqijia Town ,Changping district, Beijing, China

VASUDHA PHARMA CHEM LIMITED: Tel:+91-40-23812046, 23814987, 23711715, 23711717; Address: 78/A, Vengalrao nagar,Hyderabad - 500 038.Andhra Pradesh, INDIA.

SINOCO CHEMICAL CO., LIMITED: Tel:+86-571-81956191, 81956192; Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China.

Losartan potassium cas no:124750-99-8

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