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Hazard Xn: Harmful;
Risk R22
Safety
Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of Br− and NOx. See also ESTERS.
Safety Information of Piptal (CAS NO.125-51-9):
Hazard Codes: Xn
Risk Statements: 22
22: Harmful if swallowed
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LDLo | intravenous | 20mg/kg (20mg/kg) | VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Journal of Pharmacology and Experimental Therapeutics. Vol. 112, Pg. 64, 1954. |
guinea pig | LD50 | intravenous | 22mg/kg (22mg/kg) | Compilation of LD50 Values of New Drugs. | |
guinea pig | LD50 | oral | > 500mg/kg (500mg/kg) | Compilation of LD50 Values of New Drugs. | |
mouse | LD50 | intravenous | 18mg/kg (18mg/kg) | Compilation of LD50 Values of New Drugs. | |
mouse | LD50 | oral | 1140mg/kg (1140mg/kg) | Compilation of LD50 Values of New Drugs. | |
rat | LD50 | intravenous | 18mg/kg (18mg/kg) | "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 97, 1969. | |
rat | LD50 | oral | 916mg/kg (916mg/kg) | "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 97, 1969. | |
rat | LD50 | subcutaneous | 904mg/kg (904mg/kg) | Compilation of LD50 Values of New Drugs. |
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