Vinorelbine tartrate cas no:125317-39-7
Synonyms: Vinorelbine ditartrate (JAN);Navelbine (TN);Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-((2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino(4,3-b)indol-8-yl)-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2beta,3beta,4beta,5alpha,12R,19alpha)-, (2R,3R)-2,3-dihydroxybutanedioate (1:2) (salt);KW 2307;Navelbine;Nor-5-anhydrovinblastine ditartrate;C-Norvincaleukoblastine, 3,4-didehydro-4-deoxy-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:2) (salt);Vinorelbine ditartrate;Vinorelbine ditartate;3', 4'-didehydro-4'-deoxy- C '-norvincaleukoblastine;Vinorelbineditartrate;Vinorelbine tartrate, USP;
NameVinorelbine tartrate
CAS125317-39-7
SynonymsVinorelbine ditartrate (JAN);Navelbine (TN);Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-((2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino(4,3-b)indol-8-yl)-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2beta,3beta,4beta,5alpha,12R,19alpha)-, (2R,3R)-2,3-dihydroxybutanedioate (1:2) (salt);KW 2307;Navelbine;Nor-5-anhydrovinblastine ditartrate;C-Norvincaleukoblastine, 3,4-didehydro-4-deoxy-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:2) (salt);Vinorelbine ditartrate;Vinorelbine ditartate;3', 4'-didehydro-4'-deoxy- C '-norvincaleukoblastine;Vinorelbineditartrate;Vinorelbine tartrate, USP;
Molecular FormulaC45H54N4O8.2(C4H6O6)
Molecular Weight1079.10594
Appearancewhite to off-white crystalline powder
refractive index1.675
storage temp2-8°C
Hazard Xi:Irritant
Risk R43
Safety
Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx.
Hazard Codes:?
Xi
The Risk Statements information:
43:? May cause sensitization by skin contact?
The Safety Statements information:
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36:? Wear suitable protective clothing?
WGK Germany: 3
| 1. |
??? |
ivn-rat TDLo:2?mg/kg (female 7-16D post):REP
|
??? |
KSRNAM ?? Kiso to Rinsho. Clinical Report. 27 (1993),1375. |
