1H-Imidazole-5-propanamide,N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-a-[[(2S)-2-[[(1,1-dimethylethyl)sulfonyl]methyl]-1-oxo-3-phenylpropyl]amino]-,(aS)- cas no:126222-34-2

Name1H-Imidazole-5-propanamide,N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-a-[[(2S)-2-[[(1,1-dimethylethyl)sulfonyl]methyl]-1-oxo-3-phenylpropyl]amino]-,(aS)-
CAS126222-34-2
Synonyms1H-Imidazole-4-propanamide,N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-a-[[(2S)-2-[[(1,1-dimethylethyl)sulfonyl]methyl]-1-oxo-3-phenylpropyl]amino]-,(aS)- (9CI);1H-Imidazole-4-propanamide, N-[1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-a-[[2-[[(1,1-dimethylethyl)sulfonyl]methyl]-1-oxo-3-phenylpropyl]amino]-,[1S-[1R*[R*(R*)],2S*,3R*]]-;Remikiren;Ro 42-5892;Ro 42-5892/001;
Molecular FormulaC33H50 N4 O6 S
Molecular Weight630.8383

refractive index1.581

CHEMICAL IDENTIFICATION

RTECS NUMBER :

NI8252250

CHEMICAL NAME :

1H-Imidazole-4-propanamide, N-(1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypr opyl)- alpha-((2-(((1,1-dimethylethyl)sulfonyl)methyl)-1-oxo -3-phenylpropyl)amino )-, (1S-(1R*(R*(R*)),2S*,3R*))-

CAS REGISTRY NUMBER :

126222-34-2

LAST UPDATED :

199801

DATA ITEMS CITED :

1

MOLECULAR FORMULA :

C33-H50-N4-O6-S

MOLECULAR WEIGHT :

630.93

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

23 mg/kg

TOXIC EFFECTS :

Gastrointestinal - hypermotility, diarrhea

REFERENCE :

CLPTAT Clinical Pharmacology and Therapeutics (St. Louis). (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1960- Volume(issue)/page/year: 53,585,1993