Erythromycin ethylsuccinate cas no:1264-62-6

NameErythromycin ethylsuccinate
CAS1264-62-6
SynonymsDurapaediat;E-Mycin e;Eritrocina;EryPed;ErythroES;Erythro-Holz;Erythrocin ethyl succinate;Esinol;Evesin;Refkas;Sigapedil;Erythromycinethyl succinate (6CI);Erythromycin, 2'-(ethyl succinate) (7CI);Succinic acid, ethyl ester, monoester with erythromycin (8CI);Anamycin;Arpimycin;
EINECS(EC#)215-033-8
Molecular FormulaC₄₃H₇₅NO₁₆
Molecular Weight862.0527

AppearanceWhite to yellowish Crystalline solid
storage tempKeep in a cool, dry, well-ventilated area in a sealed container.

Hazard Xn:Harmful
Risk R42/43
Safety

Safety Information of Erythromycin ethylsuccinate (CAS NO.1264-62-6):
Hazard Codes: Xn,Xi
Risk Statements: 42/43-36/37/38??
Safety Statements: 36-26
WGK Germany: 2
RTECS: WM9800000
Hazardous Substances Data: 1264-62-6(Hazardous Substances Data)??

CHEMICAL IDENTIFICATION

RTECS NUMBER :

WM9800000

CHEMICAL NAME :

Succinic acid, monoethyl ester, monoester with erythromycin

CAS REGISTRY NUMBER :

1264-62-6

BEILSTEIN REFERENCE NO. :

0077638

LAST UPDATED :

199612

DATA ITEMS CITED :

5

MOLECULAR FORMULA :

C43-H75-N-O16

MOLECULAR WEIGHT :

862.19

WISWESSER LINE NOTATION :

T-14-VO GVTJ C2 DQ D1 EQ F1 H1 JQ J1 L1 N1 KO- BT6OTJ CQ DN1&1 F1& MO- FT6OTJ B1 CQ DO1 D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - child

DOSE/DURATION :

420 mg/kg/7D-I

TOXIC EFFECTS :

Gastrointestinal - nausea or vomiting Liver - other changes

REFERENCE :

CMAJAX Canadian Medical Association Journal. (Canadian Medical Assoc., POB 8650, Ottawa, ON K1G 0G8, Canada) V.1- 1911- Volume(issue)/page/year: 129,411,1983

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

5714 ug/kg

TOXIC EFFECTS :

Behavioral - ataxia

REFERENCE :

AJEMEN American Journal of Emergency Medicine. (WB Saunders, Philadelphia, PA) V.1- 1983- Volume(issue)/page/year: 10,616,1992

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

4167 mg/kg

TOXIC EFFECTS :

Gastrointestinal - hypermotility, diarrhea

REFERENCE :

TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 9,445,1966

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

>10 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,126,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0949 No. of Facilities: 113 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 3065 (estimated) No. of Female Employees: 1433 (estimated)