Propanoic acid,2,2-dichloro-, sodium salt (1:1) cas no:127-20-8
Synonyms: Propanoicacid, 2,2-dichloro-, sodium salt (9CI); Propionic acid, 2,2-dichloro-, sodiumsalt (8CI); 2,2-DPA Na salt; 2,2-Dichloropropionic acid sodium salt;Antigramigna; Basfapon; Dalapon sodium; Dalapon sodium salt; Dikopan; Dowpon;Dowpon S; Gramevin; Omnidel; Omnidel Spezial; Propinate; Radapon; SYS 67Omnidel; Sodium 2,2-dichloropropionate; Sodium 2,2-dichloropropionic acid;Sodium Dalapon; Sodium dichloropropionate; Sodium a,a-dichloropropionate; Tafapon; a,a-Dichloropropionic acid sodiumsalt
NamePropanoic acid,2,2-dichloro-, sodium salt (1:1)
CAS127-20-8
SynonymsPropanoicacid, 2,2-dichloro-, sodium salt (9CI); Propionic acid, 2,2-dichloro-, sodiumsalt (8CI); 2,2-DPA Na salt; 2,2-Dichloropropionic acid sodium salt;Antigramigna; Basfapon; Dalapon sodium; Dalapon sodium salt; Dikopan; Dowpon;Dowpon S; Gramevin; Omnidel; Omnidel Spezial; Propinate; Radapon; SYS 67Omnidel; Sodium 2,2-dichloropropionate; Sodium 2,2-dichloropropionic acid;Sodium Dalapon; Sodium dichloropropionate; Sodium a,a-dichloropropionate; Tafapon; a,a-Dichloropropionic acid sodiumsalt
EINECS(EC#)204-828-5
Molecular FormulaC3H4 Cl2 O2 . Na
Molecular Weight164.95
storage temp+4°C
Hazard Xi: Irritant;
Risk R20/21/22
Safety Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of Na2O and Cl−.
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UF1225000
- CHEMICAL NAME :
- Propionic acid, 2,2-dichloro-, sodium salt
- CAS REGISTRY NUMBER :
- 127-20-8
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 26
- MOLECULAR FORMULA :
- C3-H3-Cl2-O2.Na
- MOLECULAR WEIGHT :
- 164.95
- WISWESSER LINE NOTATION :
- OVXGG1 &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3860 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >6 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3650 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 3400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 3400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 5600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - domestic
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- >20 gm/m3/8H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 6600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 57246 mg/kg/9W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight
Endocrine - changes in thyroid weight
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 26 gm/kg/22W-I
- TOXIC EFFECTS :
- Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Endocrine - other changes
Endocrine - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 36500 mg/kg/2Y-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in bladder weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 26 gm/kg/1Y-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in bladder weight
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- REFERENCE :
- TGANAK Tsitologiya i Genetika. Cytology and Genetics. For English
translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1- 1967- Volume(issue)/page/year: 16(1),45,1982
*** REVIEWS ***
TOXICOLOGY REVIEW
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44
Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year:
53,109,1974
TOXICOLOGY REVIEW
DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.)
V.1-77, 1893-1970. Volume(issue)/page/year: 80,485,1973
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-GERMANY:TWA 1 ppm (6 mg/m3) JAN 1993
OEL-SWITZERLAND:TWA 1 ppm (6 mg/m3) JAN 1993
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 83056
No. of Facilities: 534 (estimated)
No. of Industries: 4
No. of Occupations: 2
No. of Employees: 9622 (estimated)