Benzenesulfonamide,4-amino-N-2-pyridinyl-, sodium salt (1:1) cas no:127-57-1

Synonyms: Benzenesulfonamide,4-amino-N-2-pyridinyl-, monosodium salt (9CI); Sodium, (N1-2-pyridylsulfanilamido)-(7CI); Sulfanilamide, N1-2-pyridyl-, monosodium salt (8CI); Sulfapyridinesodium deriv (6CI); 2-Sulfanilamidopyridine sodium salt; Izopiridina; Sodiumsulfapyridine; Soludagenan; Sulfapyridine sodium

Identification

NameBenzenesulfonamide,4-amino-N-2-pyridinyl-, sodium salt (1:1)
CAS127-57-1
SynonymsBenzenesulfonamide,4-amino-N-2-pyridinyl-, monosodium salt (9CI); Sodium, (N1-2-pyridylsulfanilamido)-(7CI); Sulfanilamide, N1-2-pyridyl-, monosodium salt (8CI); Sulfapyridinesodium deriv (6CI); 2-Sulfanilamidopyridine sodium salt; Izopiridina; Sodiumsulfapyridine; Soludagenan; Sulfapyridine sodium
EINECS(EC#)204-850-5
Molecular FormulaC11H11 N3 O2 S . Na
Molecular Weight271.29

Safety Data

Safety

Moderately toxic by ingestion, intraperitoneal, subcutaneous, intravenous, and parenteral routes. When heated to decomposition it emits very toxic fumes of NO_x, Na₂O, and SO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
guinea pig	LD50	intravenous	693mg/kg (693mg/kg)	Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940.
monkey	LDLo	intravenous	600mg/kg (600mg/kg)	Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940.
mouse	LD50	intramuscular	1096mg/kg (1096mg/kg)	Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940.
mouse	LD50	intraperitoneal	910mg/kg (910mg/kg)	Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940.
mouse	LD50	intravenous	696mg/kg (696mg/kg)	Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940.
mouse	LD50	oral	2gm/kg (2000mg/kg)	Journal of Pharmacology and Experimental Therapeutics. Vol. 68, Pg. 259, 1940.
mouse	LD50	parenteral	1gm/kg (1000mg/kg)	Proceedings of the Society for Experimental Biology and Medicine. Vol. 43, Pg. 328, 1940.
mouse	LD50	subcutaneous	872mg/kg (872mg/kg)	Journal of Pharmacology and Experimental Therapeutics. Vol. 71, Pg. 138, 1941.
rat	LD50	intravenous	648mg/kg (648mg/kg)	Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 33, Pg. 80, 1944.
rat	LD50	oral	2994mg/kg (2994mg/kg)	Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940.
rat	LDLo	intraperitoneal	1120mg/kg (1120mg/kg)	Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 15, 1940.

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