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Ursodeoxycholic acid cas no:128-13-2

Synonyms: (4R)-4-[(3R,5S,7S,8R,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate;Cholan-24-oic acid, 3,7-dihydroxy-, (3-.alpha.,5-.beta., 7-.beta.)-;Cholan-24-oic acid,3,7-dihydroxy-,(3R,5a,- 7a)-;UDCA;5.beta.-Chol-24-oic acid-3.alpha., 7.beta.-diol;Arsacol;Ursochol;Antigall;Urso (TN);Ursodiol;Antigall (TN);Actigall;Urso;Litursol;Deursil;Desocol;Ursodeoxycholic acid (JP14);Delursan;Ursodiol (USP);deoxy-;Urso Deoxy Cholic Acid;7beta-Hydroxylithocholic acid;Ursodeoxycholoc acid;

Identification
NameUrsodeoxycholic acid
CAS128-13-2
Synonyms(4R)-4-[(3R,5S,7S,8R,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate;Cholan-24-oic acid, 3,7-dihydroxy-, (3-.alpha.,5-.beta., 7-.beta.)-;Cholan-24-oic acid,3,7-dihydroxy-,(3R,5a,- 7a)-;UDCA;5.beta.-Chol-24-oic acid-3.alpha., 7.beta.-diol;Arsacol;Ursochol;Antigall;Urso (TN);Ursodiol;Antigall (TN);Actigall;Urso;Litursol;Deursil;Desocol;Ursodeoxycholic acid (JP14);Delursan;Ursodiol (USP);deoxy-;Urso Deoxy Cholic Acid;7beta-Hydroxylithocholic acid;Ursodeoxycholoc acid;
EINECS(EC#)204-879-3
Molecular FormulaC24H40O4
Molecular Weight392.58
Chemical Properties
Appearancewhite crystalline powder
alpha60 o (C=2, ETOH)
refractive index60.5 ° (C=2, EtOH)
storage tempStore in a tightly closed container. Store in a cool, dry area away from incompatible substances.
Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Hazard Codes:?IrritantXi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26?
S24/25:Avoid contact with skin and eyes.?
S36:Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 2
RTECS: FZ2000000
F: 10
Poison by intraperitoneal and intravenous routes. Experimental teratogenic and reproductive effects. Mutation data reported. Stimulates the flow of bile to the duodenum (a cholagogic). When heated to decomposition it emits acrid smoke and irritating fumes.


Toxicity
1. ???

mmo-sat 40?mg/L

??? MUREAV ?? Mutation Research. 158 (1985),45.
2. ???

orl-rat TDLo:11,900?mg/kg (4-20D preg):TER

??? AIPTAK ?? Archives Internationales de Pharmacodynamie et de Therapie. 246 (1980),149.
3. ???

orl-rat LD50:4600?mg/kg

??? BCFAAI ?? Bollettino Chimico Farmaceutico. 126 (1987),282.
4. ???

ipr-rat LD50:890?mg/kg

??? NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),95.
5. ???

ivn-rat LD50:310?mg/kg

??? NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),95.
6. ???

ivn-mus LD50:240?mg/kg

??? NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),95.

supplier list

Extrasynthese
Tel:+33-(0)478982034
Address: Zi Lyon Nord Impasse Jacquard BP 62 69730 Genay
Lotus chemical (HK) Limited
Tel:+86-(23)-86092822
Address: 602 Room, 172#, Gaoyan Road, Yubei, Chongqing 401120,
PharmaZell GmbH
Tel:+49-(8035)-88 176
Address: Rosenheimer Str. 43, Raubling D-83064,
Global Pharma Sourcing, LLC
Tel:484-467-9549
Address:
Suzhou Tianlu Bio-pharmaceutical Co., Ltd.
Tel:+86-(512)-65657388
Address: 1128 Yin Zhong south Road Wuzhong Economic Development Zone, Suzhou, Jiangsu 215124,
Raytop Enterprises Limited
Tel:+86-(592)-7698791
Address: 404, #21 Yinhu Xili, Tong?an District, Xiamen, Fujian 361005,
Wuxi Mizat Chemical Technology Co., Ltd
Tel:+86-(510)-86106900
Address: No.205,zhencheng Road, HI-TECT District, Wuxi, Jiangsu,
Beijing HuameiHuli Biochem Ltd
Tel:010-86181995
Address: Beijing TongZhou District
Hangzhou Hysen Pharma Co.,Ltd
Tel:0571-89937472
Address: ROOM 808, C# Zi Jin PLAZA , NO. 701, Gu'Dun ROAD
Hubei Hetian Chemical Co.,Ltd
Tel:0719-5253313
Address: danzhaolu
HBCChem, Inc.
Tel:+1-510-219-6317
Address:
lotuschem
Tel:852-29738324
Address: Rm. 907. JCD116 Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong
Hangzhou Fu Ma Chemical Co., Ltd.
Tel:86 571 82705292, 86 571 82755660
Address: Hangzhou
Ningbo Fengrui Fine Chemical Ltd.
Tel:+86-574-87720208
Address: Caihong North Road
Suzhou Tianlu Bio-pharmaceutical Co.,Ltd.
Tel:+86-512-65657388
Address: 1128 Yinzhong South Road, Wuzhong Economic Development Zone, Suzhou

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