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Ursodeoxycholic acid cas no:128-13-2

Synonyms: (4R)-4-[(3R,5S,7S,8R,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate;Cholan-24-oic acid, 3,7-dihydroxy-, (3-.alpha.,5-.beta., 7-.beta.)-;Cholan-24-oic acid,3,7-dihydroxy-,(3R,5a,- 7a)-;UDCA;5.beta.-Chol-24-oic acid-3.alpha., 7.beta.-diol;Arsacol;Ursochol;Antigall;Urso (TN);Ursodiol;Antigall (TN);Actigall;Urso;Litursol;Deursil;Desocol;Ursodeoxycholic acid (JP14);Delursan;Ursodiol (USP);deoxy-;Urso Deoxy Cholic Acid;7beta-Hydroxylithocholic acid;Ursodeoxycholoc acid;

Identification
NameUrsodeoxycholic acid
CAS128-13-2
Synonyms(4R)-4-[(3R,5S,7S,8R,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate;Cholan-24-oic acid, 3,7-dihydroxy-, (3-.alpha.,5-.beta., 7-.beta.)-;Cholan-24-oic acid,3,7-dihydroxy-,(3R,5a,- 7a)-;UDCA;5.beta.-Chol-24-oic acid-3.alpha., 7.beta.-diol;Arsacol;Ursochol;Antigall;Urso (TN);Ursodiol;Antigall (TN);Actigall;Urso;Litursol;Deursil;Desocol;Ursodeoxycholic acid (JP14);Delursan;Ursodiol (USP);deoxy-;Urso Deoxy Cholic Acid;7beta-Hydroxylithocholic acid;Ursodeoxycholoc acid;
EINECS(EC#)204-879-3
Molecular FormulaC24H40O4
Molecular Weight392.58
Chemical Properties
Appearancewhite crystalline powder
alpha60 o (C=2, ETOH)
refractive index60.5 ° (C=2, EtOH)
storage tempStore in a tightly closed container. Store in a cool, dry area away from incompatible substances.
Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Hazard Codes:?IrritantXi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26?
S24/25:Avoid contact with skin and eyes.?
S36:Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 2
RTECS: FZ2000000
F: 10
Poison by intraperitoneal and intravenous routes. Experimental teratogenic and reproductive effects. Mutation data reported. Stimulates the flow of bile to the duodenum (a cholagogic). When heated to decomposition it emits acrid smoke and irritating fumes.


Toxicity
1. ???

mmo-sat 40?mg/L

??? MUREAV ?? Mutation Research. 158 (1985),45.
2. ???

orl-rat TDLo:11,900?mg/kg (4-20D preg):TER

??? AIPTAK ?? Archives Internationales de Pharmacodynamie et de Therapie. 246 (1980),149.
3. ???

orl-rat LD50:4600?mg/kg

??? BCFAAI ?? Bollettino Chimico Farmaceutico. 126 (1987),282.
4. ???

ipr-rat LD50:890?mg/kg

??? NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),95.
5. ???

ivn-rat LD50:310?mg/kg

??? NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),95.
6. ???

ivn-mus LD50:240?mg/kg

??? NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),95.

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Shandong Aocter Chemical Co.,Ltd.
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Aceto Corporation
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Hangzhou sanli industry co.,ltd
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HYLEN CO., LTD.
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Shanghai Standard Biotech Co., Ltd.
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SINOVA
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AFINE CHEMICALS LIMITED
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Boc Sciences
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Shijiazhuang Sdyano Fine Chemical Co., Ltd
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Xi'an Lyphar Biotech Co., Ltd.
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Wuhan Dahua Weiye Pharmaceutical Co.,Ltd
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Hangzhou Utanpharma biology co,.Ltd
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Nanjing Bangnuo Biotechnology Co., Ltd.
Tel:86-25-52113793
Address: Room 901 Tianqinwan Garden NO.1008 Ssangyong Avenu
Nanjing Bangnuo Biotechnology Co., Ltd.
Tel:86-25-52113793
Address: Room 901 Tianqinwan Garden NO.1008 Ssangyong Avenu

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