Pregnan-20-one,3-hydroxy-, (3a,5b)- cas no:128-20-1

NamePregnan-20-one,3-hydroxy-, (3a,5b)-
CAS128-20-1
Synonyms5b-Pregnan-20-one, 3a-hydroxy- (6CI,8CI);3-Deoxo-3a-hydroxy-5b-dihydroprogesterone;3a,5b-Pregnanolone;3a,5b-Tetrahydroprogesterone;3a-Hydroxy-20-oxo-5b-pregnane;3a-Hydroxy-5b,17b-pregnan-20-one;3a-Hydroxy-5b-pregnan-20-one;3a-Hydroxy-5b-tetrahydroprogesterone;5b-Pregnan-3a-ol-20-one;5b-Pregnane-3a-ol-20-one;Eltanolone;KABI2213;NSC 82867;Pregnan-3a-ol-20-one;Pregnanolone;Pregnanolone II;SKF 6455;U 2340;
Molecular FormulaC₂₁H₃₄O₂
Molecular Weight318.50

AppearanceSolid.
refractive index1.524
storage tempKeep tightly closed. Store in a cool dry place.

Hazard Xn: Harmful;
Risk R40

CHEMICAL IDENTIFICATION

RTECS NUMBER :

TU4384000

CHEMICAL NAME :

5-beta-Pregnan-20-one, 3-alpha-hydroxy-

CAS REGISTRY NUMBER :

128-20-1

LAST UPDATED :

199612

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C21-H34-O2

MOLECULAR WEIGHT :

318.55

WISWESSER LINE NOTATION :

L E5 B666TJ A1 E1 FV1 OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

27500 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,117,1968

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

66 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,117,1968