Sodium saccharin cas no:128-44-9
Synonyms: 1,2-Benzisothiazol-3(2H)-one,1,1-dioxide, sodium salt (1:1);Saccharine Sodium USP;1,2-Benzisothiazol-3(2H)-one,1,1-dioxide, sodium salt (9CI);1,2-Benzisothiazolin-3-one, 1,1-dioxide, sodiumderiv. (7CI);1,2-Benzisothiazolin-3-one, 1,1-dioxide, sodium salt (8CI);Saccharin, sodium deriv. (6CI);1,2-Benzothiazol-3(2H)-one 1,1-dioxide sodiumsalt;Cristallose;Crystallose;Kristallose;Saxin;Sodium o-benzosulfimide;Sodiumo-sulfobenzimide;Sucram C 150;Sweeta;Sykose;Willosetten;o-Benzoylsulfimide sodium salt;
NameSodium saccharin
CAS128-44-9
Synonyms1,2-Benzisothiazol-3(2H)-one,1,1-dioxide, sodium salt (1:1);Saccharine Sodium USP;1,2-Benzisothiazol-3(2H)-one,1,1-dioxide, sodium salt (9CI);1,2-Benzisothiazolin-3-one, 1,1-dioxide, sodiumderiv. (7CI);1,2-Benzisothiazolin-3-one, 1,1-dioxide, sodium salt (8CI);Saccharin, sodium deriv. (6CI);1,2-Benzothiazol-3(2H)-one 1,1-dioxide sodiumsalt;Cristallose;Crystallose;Kristallose;Saxin;Sodium o-benzosulfimide;Sodiumo-sulfobenzimide;Sucram C 150;Sweeta;Sykose;Willosetten;o-Benzoylsulfimide sodium salt;
EINECS(EC#)204-886-1
Molecular FormulaC7H4NNaO3S
Molecular Weight205.16
AppearanceWhite crystalline powder
storage temp0-6°C
Safety
Safety Statements: 24/25
S24/25: Avoid contact with skin and eyes.
WGK Germany: 2
RTECS: DE4550000
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Moderately toxic by ingestion and intraperitoneal routes. A promoter. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SOx, Na2O, and NOx.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
6gm/kg (6000mg/kg) |
? |
United States Patent Document. Vol. #4869913, |
| mouse |
LD50 |
oral |
17500mg/kg (17500mg/kg) |
? |
Food and Cosmetics Toxicology. Vol. 6, Pg. 313, 1968. |
| mouse |
LDLo |
subcutaneous |
7gm/kg (7000mg/kg) |
? |
Yakkyoku. Pharmacy. Vol. 32, Pg. 1367, 1981. |
| rabbit |
LDLo |
oral |
4gm/kg (4000mg/kg) |
? |
Yakkyoku. Pharmacy. Vol. 32, Pg. 1367, 1981. |
| rat |
LD50 |
intraperitoneal |
7100mg/kg (7100mg/kg) |
? |
Food and Cosmetics Toxicology. Vol. 6, Pg. 313, 1968. |
| rat |
LD50 |
oral |
14200mg/kg (14200mg/kg) |
? |
Food and Cosmetics Toxicology. Vol. 6, Pg. 313, 1968. |
