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Pyrene cas no:129-00-0

Synonyms: Benzo[def]phenanthrene; Pyrenepract; Pyrene (purity)

Identification
NamePyrene
CAS129-00-0
SynonymsBenzo[def]phenanthrene; Pyrenepract; Pyrene (purity)
EINECS(EC#)204-927-3
Molecular FormulaC16H10
Molecular Weight202.25
Chemical Properties
AppearanceYellow green crystal
refractive index1.851
storage tempAPPROX 4°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T+:Verytoxic;N:Dangerousfortheenvironment;
Risk R26;R36/37/38;R50/53
Safety

Poison by inhalation. Moderately toxic by ingestion and intraperitoneal routes. A skin irritant. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes: DangerousN,VeryT+,ToxicT,FlammableF,HarmfulXn
Risk Statements: 50/53-36/37/38-26-39/23/24/25-23/24/25-11-63-43-45-67-65-38 
R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R36/37/38: Irritating to eyes, respiratory system and skin. 
R26: Very toxic by inhalation. 
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed. 
R11: Highly flammable. 
R63: Possible risk of harm to the unborn child. 
R43: May cause sensitization by skin contact. 
R45: May cause cancer. 
R67: Vapours may cause drowsiness and dizziness. 
R65: Harmful: may cause lung damage if swallowed. 
R38: Irritating to skin.
Safety Statements: 60-61-45-36/37-28A-22-16-7-24/25-23-53-62 
S60: This material and its container must be disposed of as hazardous waste. 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37: Wear suitable protective clothing and gloves. 
S22: Do not breathe dust. 
S16: Keep away from sources of ignition. 
S7: Keep container tightly closed. 
S24/25: Avoid contact with skin and eyes. 
S23: Do not breathe vapour. 
S53: Avoid exposure - obtain special instructions before use. 
S62: If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label.
RIDADR: UN 3077 9/PG 3
WGK Germany: 2
RTECS: UR2450000
HazardClass: 6.1(b)
PackingGroup: III


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 514mg/kg (514mg/kg)   Progress in Mutation Research. Vol. 1, Pg. 682, 1981.
mouse LD50 oral 800mg/kg (800mg/kg) SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(2), Pg. 59, 1971.
rat LC50 inhalation 170mg/m3 (170mg/m3) SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(2), Pg. 59, 1971.
rat LD50 oral 2700mg/kg (2700mg/kg) SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(2), Pg. 59, 1971.

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