129-49-7|METHYSERGIDE DIMALEATEProducts Supply - Chemical intermediates Network

METHYSERGIDE DIMALEATE cas no:129-49-7

Synonyms: 1-(hydroxymethyl)propylamideof1-methyl-(+)-lysergicacidhydrogenmaleate;deseril-retard;ergoline-8-beta-carboxamide,9,10-didehydro-n-(1-(hydroxymethyl)propyl)-1,6-dim;maleate(1:1)(salt);methysergidebimaleate;methysergidedimaleate;methysergidehydrogenmaleate;n-((1-hydroxymethyl)propyl)-1-methyl-lysergamidmaleate

Identification

NameMETHYSERGIDE DIMALEATE
CAS129-49-7
Synonyms1-(hydroxymethyl)propylamideof1-methyl-(+)-lysergicacidhydrogenmaleate;deseril-retard;ergoline-8-beta-carboxamide,9,10-didehydro-n-(1-(hydroxymethyl)propyl)-1,6-dim;maleate(1:1)(salt);methysergidebimaleate;methysergidedimaleate;methysergidehydrogenmaleate;n-((1-hydroxymethyl)propyl)-1-methyl-lysergamidmaleate
EINECS(EC#)204-950-9
Molecular FormulaC₂₁H₂₇N₃O₂?C₄H₄O₄
Molecular Weight469.53014

Chemical Properties

Appearancewhite to off-white

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard T: Toxic;
Risk R25
Safety

Hazard Codes: T Toxic
Risk Statements of Methysergide dimaleate (CAS NO.129-49-7): 25
R25: Toxic if swallowed.
Safety Statements: 45
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: KE5410000
HazardClass: 6.1(b)
PackingGroup: III
Poison by ingestion and intravenous routes. Experimental reproductive effects. Human mutation effects reported. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intravenous	185mg/kg (185mg/kg)	"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 101, 1972.
mouse	LD50	oral	581mg/kg (581mg/kg)	"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 101, 1972.
rabbit	LD50	intravenous	28mg/kg (28mg/kg)	"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 101, 1972.
rat	LD50	intravenous	125mg/kg (125mg/kg)	"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 101, 1972.
rat	LD50	oral	200mg/kg (200mg/kg)	"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 101, 1972.

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METHYSERGIDE DIMALEATE cas no:129-49-7

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