[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-,(3Z,5R,6R,14aR,14bR)- cas no:130-01-8

Name[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-,(3Z,5R,6R,14aR,14bR)-
CAS130-01-8
SynonymsSenecionan-11,16-dione,12-hydroxy-; Senecionine (6CI,7CI,8CI); (-)-Senecionine; Aureine; NSC 89935;Senecionin; [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-,[5R-(3Z,5R*,6R*,14aR*,14bR*)]-
Molecular FormulaC18H25 N O5
Molecular Weight335.39

refractive index1.57
storage temp−20°C

Hazardclass6.1(a)

Hazard T
Risk R25
Safety

Poison by intravenous, intraperitoneal, and possibly other routes. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes: T
Risk Statements: 25 
R25: Toxic if swallowed
Safety Statements: 45 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible)
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: VT5710000
F: 10-23
HazardClass: 6.1(a)
PackingGroup: II

1.		sln-dmg-par 20 µmol/L		ZEVBA5    Zeitschrift fuer Verebungslehre. 91 (1960),74.
2.		dns-rat:lvr 700 nmol/L		CNREA8    Cancer Research. 45 (1985),3125.
3.		dnd-mus-ipr 90 mg/kg		TOXID9    Toxicologist. 1 (1981),42.
4.		ipr-rat LDLo:33 mg/kg		CBINA8    Chemico-Biological Interactions. 12 (1976),299.
5.		ivn-rat LD50:41,200 µg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 87 (1946),382.
6.		unr-rat LD50:40 mg/kg		CNREA8    Cancer Research. 28 (1968),2237.
7.		ivn-mus LD50:64 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 75 (1942),69.
8.		ivn-ham LD50:61 mg/kg		RETOAE    Research Today. 5 (1949),53.