Welcome to hiintermediates.com,intermediates trading platform
Home > products > thioridazine hydrochloride

thioridazine hydrochloride cas no:130-61-0

Synonyms: THIORIDAZINE HCL; 10-[2-(1-METHYL-2-PIPERIDYL)ETHYL]-2-(METHYLTHIO)-10H-PHENOTHIAZINE HYDROCHLORIDE; 10-[2-(1-METHYL-2-PIPERIDYL)-ETHYL]-2-[METHYLTHIOL]-PHENOTHIAZINE HYDROCHLORIDE; LABOTEST-BB LT00451961; 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)-10h-phenothiazinmono; 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid mellarilhydrochloride melleril(tablet) usafsz-3 ThioridazinHCl Thioridazinhydrochlorid 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride Orsanil Ridazin Stalleril 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride THIORIDAZINEHYDROCHLORIDE,USP 10-[3-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine hydrochloride; 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, monohydrochloride (9CI); Novoridazine

Identification
Namethioridazine hydrochloride
CAS130-61-0
SynonymsTHIORIDAZINE HCL; 10-[2-(1-METHYL-2-PIPERIDYL)ETHYL]-2-(METHYLTHIO)-10H-PHENOTHIAZINE HYDROCHLORIDE; 10-[2-(1-METHYL-2-PIPERIDYL)-ETHYL]-2-[METHYLTHIOL]-PHENOTHIAZINE HYDROCHLORIDE; LABOTEST-BB LT00451961; 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)-10h-phenothiazinmono; 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid mellarilhydrochloride melleril(tablet) usafsz-3 ThioridazinHCl Thioridazinhydrochlorid 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride Orsanil Ridazin Stalleril 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride THIORIDAZINEHYDROCHLORIDE,USP 10-[3-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine hydrochloride; 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, monohydrochloride (9CI); Novoridazine
EINECS(EC#)204-992-8
Molecular FormulaC21H26N2S2?HCl
Molecular Weight407.03
Chemical Properties
AppearanceWhite to off-white solid.
Safety Data

Hazard Xn:Harmful;N:Dangerousfortheenvironment;
Risk R22;R36/37/38;R50/53
Safety

Poison by ingestion and intravenous routes. Human systemic effects: evidence of thyroid hyperfunction, increased body temperature, pulse rate increase. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl.
Hazard Codes: HarmfulXn,DangerousN
Risk Statements:
R22: Harmful if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
S60: This material and its container must be disposed of as hazardous waste. 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 160mg/kg (160mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 53, 1972.
mouse LD50 intraperitoneal 100mg/kg (100mg/kg)   National Technical Information Service. Vol. AD277-689,
mouse LD50 intravenous 33mg/kg (33mg/kg)   Therapie. Vol. 14, Pg. 793, 1959.
mouse LD50 oral 360mg/kg (360mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 53, 1972.
rabbit LD50 intravenous 26mg/kg (26mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 53, 1972.
rabbit LD50 oral 1100mg/kg (1100mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 53, 1972.
rat LD50 intravenous 71mg/kg (71mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 53, 1972.
rat LD50 oral 1060mg/kg (1060mg/kg)   Drugs in Japan Vol. 6, Pg. 458, 1982.
women TDLo oral 864mg/kg/18D- (864mg/kg) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

ENDOCRINE: EVIDENCE OF THYROID HYPERFUNCTION
Postgraduate Medical Journal. Vol. 60, Pg. 445, 1984.

supplier list

Tianjin Harmony Technology Development Co., Ltd.
Tel:
Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China
INFA S.P.A.
Tel:+39-02-777281
Address: Via Salvini 10, 20122 Milan (Italy)
Chongqing Chuandong Chemical Co.Ltd
Tel:+86-(23)-62950880
Address: 20 Zhongyao St., Baishatuo, Nan'an Dist, Chongqing,
Dishman Europe Ltd.
Tel:+44-(207)-3230608
Address: Suite 4, De Walden Court, 85 New Cavendish Street, London W1W 6XD,
Santa Cruz Biotechnology, Inc.
Tel:+1-(831)-457-3800
Address: 2145, Delaware Avenue, Santa Cruz, California 95060,
Nanjing Newell Chemical Co.,Ltd
Tel:0086-25-84216562
Address: No.98 Jiangye Road , Nanjing 210004,
Hritik Chemical Corporation
Tel:+91-(22)-6692 5779
Address: 13/B, Laxmi Industrial Estate,New Link Road, Andheri(W)., Mumbai, Maharashtra 400 053,
Chongqing Trust Long Co., Ltd.
Tel:+86-(23)-6760-5657, 6791-0421, 6707-4306
Address: 3-6-2, No.1, Xinglong Road, Longxi Town, Yubei Dist, Chongqing 401147,
Yibin JiuLing Chemical Corp.
Tel:+86-(23)-62982874
Address: Siliexiang, Gaoxian, Yibin, Sichuan,
Wuxi Feipeng Imp. & Exp. (Group) Co., Ltd.
Tel:+86-(510)-87508506
Address: 3, Nanhuan Road, Zhoutie Town, Sourtheast Suburb, Wuxi City, Jiangsu 214261,
Dishman Pharmaceuticals & Chemicals Co., Ltd.
Tel:+86-510-85840486 13771085865
Address: rm1101, times bldg, 655#Hubing rd, wuxi, china
HangZhou Peak Chemical Co.,Ltd
Tel:+86-571-88233073
Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China
Trifarma SpA
Tel:+ 39-02-57512543 39-02-9690018
Address: 20020 Ceriano Laghetto (Mi), Italy.
AOPHARM
Tel:86-311-66600578
Address: C-2103 Wonder Business Square, 15 Yuhua West Rd.
Boc Sciences
Tel:1-631-5046093
Address: 45-16 Ramsey Road Shirley, NY 11967, USA

Home   |   About Us   |   Service   |   Links   |   Add to  Favorite

Copyright©2011 HiIntermediates ICP: B2-20090288 浙ICP备09045134号-49
Tel: +86-0571-89739792