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1,1'-Biphenyl,2,2'-dichloro- cas no:13029-08-8

Synonyms: Biphenyl,2,2'-dichloro- (6CI,7CI,8CI); 2,2'-DCBP; 2,2'-Dichloro-1,1'-biphenyl;2,2'-Dichlorobiphenyl; 2,2'-Dichlorodiphenyl; NSC 59902; PCB 4;o,o'-Dichlorobiphenyl

Identification
Name1,1'-Biphenyl,2,2'-dichloro-
CAS13029-08-8
SynonymsBiphenyl,2,2'-dichloro- (6CI,7CI,8CI); 2,2'-DCBP; 2,2'-Dichloro-1,1'-biphenyl;2,2'-Dichlorobiphenyl; 2,2'-Dichlorodiphenyl; NSC 59902; PCB 4;o,o'-Dichlorobiphenyl
EINECS(EC#)215-648-1
Molecular FormulaC12H8 Cl2
Molecular Weight223.10
Chemical Properties
refractive index1.594
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass9
Safety Data

Hazard N: Dangerous for the environment;
Risk R33
Safety

Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of Cl. See also POLYCHLORINATED BIPHENYLS.
Hazard Codesof 2,2'-Dichlorobiphenyl (CAS NO.13029-08-8): DangerousN
Risk Statements: 33-50/53 
R33:Danger of cumulative effects. 
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 35-60-61 
S35:This material and its container must be disposed of in a safe way. 
S60:This material and its container must be disposed of as hazardous waste. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.


Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DV3900000
CHEMICAL NAME :
Biphenyl, 2,2'-dichloro-
CAS REGISTRY NUMBER :
13029-08-8
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C12-H8-Cl2
MOLECULAR WEIGHT :
223.10

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
150 mg/kg/3D-I
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 33,94,1975
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
25 mg/kg/20D-I
TOXIC EFFECTS :
Immunological Including Allergic - decrease in humoral immune response
REFERENCE :
JEPOEC Journal of Environmental Pathology, Toxicology and Oncology. (Chem-Orbital, POB 134, Park Forest, IL 60466) V.5(4)- 1984- Volume(issue)/page/year: 9,283,1989
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
25 mg/kg/20D-I
TOXIC EFFECTS :
Liver - other changes
REFERENCE :
JEPOEC Journal of Environmental Pathology, Toxicology and Oncology. (Chem-Orbital, POB 134, Park Forest, IL 60466) V.5(4)- 1984- Volume(issue)/page/year: 12,17,1993 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1125 mg/kg
SEX/DURATION :
female 1-3 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 40,249,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1500 mg/kg
SEX/DURATION :
female 1-3 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 40,249,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1125 mg/kg
SEX/DURATION :
female 1-3 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - parturition
REFERENCE :
BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 16,33,1976

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