1H-Purine-2,6-dione,7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-3,7-dihydro-1,3-dimethyl-,hydrochloride (1:1) cas no:13055-82-8

Name1H-Purine-2,6-dione,7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-3,7-dihydro-1,3-dimethyl-,hydrochloride (1:1)
CAS13055-82-8
Synonyms1H-Purine-2,6-dione,7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-3,7-dihydro-1,3-dimethyl-,monohydrochloride (9CI); Theophylline, 7-[3-[(b,3,5-trihydroxyphenethyl)amino]propyl]-, hydrochloride(7CI); Theophylline, 7-[3-[(b,3,5-trihydroxyphenethyl)amino]propyl]-, monohydrochloride (8CI);Asmaterolo; Bronchodil; Bronchospasmin; D 1959 HCl; Reproterol hydrochloride; W2946M
EINECS(EC#)235-942-3
Molecular FormulaC18H23 N5 O5 . Cl H
Molecular Weight425.92

Safety

Poison by intravenous route. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of HCl and NO_x. See also THEOPHYLLINE.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	160mg/kg (160mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: COMA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 45, 1977.
dog	LD50	oral	400mg/kg (400mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: COMA GASTROINTESTINAL: NAUSEA OR VOMITING	Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 45, 1977.
mouse	LD50	intravenous	148mg/kg (148mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA	Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 45, 1977.
mouse	LD50	oral	> 10gm/kg (10000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA	Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 45, 1977.
rat	LD50	intravenous	142mg/kg (142mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA	Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 45, 1977.
rat	LD50	oral	> 10gm/kg (10000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA	Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 45, 1977.