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Diatrizoate meglumine cas no:131-49-7

Synonyms: 3,5-diacetamido-2,4,6-triiodo-benzoicacicompd.with1-deoxy-1-(methylam;amidotrizoatemeglumine;angiografin;cardiografin;d-;d-glucitol,1-deoxy-1-(methylamino)-,3,5-bis(acetylamino)-2,4,6-triiodobenzo;diatrizoatemethylglucamine;gastrografin

Identification
NameDiatrizoate meglumine
CAS131-49-7
Synonyms3,5-diacetamido-2,4,6-triiodo-benzoicacicompd.with1-deoxy-1-(methylam;amidotrizoatemeglumine;angiografin;cardiografin;d-;d-glucitol,1-deoxy-1-(methylamino)-,3,5-bis(acetylamino)-2,4,6-triiodobenzo;diatrizoatemethylglucamine;gastrografin
EINECS(EC#)205-024-7
Molecular FormulaC11H9I3N2O4•C7H17NO5
Molecular Weight809.17
Safety Data

Safety

Poison by intracerebral route. Human systemic effects by subcutaneous route: kidney damage and reduced urine volume. When heated to decomposition it emits toxic fumes of I and NOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo subcutaneous 214mg/kg (214mg/kg) KIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULI

KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS

KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 392, 1969.
mouse LD50 intracrebral 80mg/kg (80mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Therapie. Vol. 26, Pg. 595, 1971.
mouse LD50 intravenous 21200mg/kg (21200mg/kg)   Drugs in Japan Vol. 6, Pg. 32, 1982.
rat LD50 intravenous 14565mg/kg (14565mg/kg)   AJR, American Journal of Roentgenology. Vol. 142, Pg. 619, 1984.
rat LD50 parenteral 44504mg/kg (44504mg/kg)   AJR, American Journal of Roentgenology. Vol. 142, Pg. 619, 1984.
rat LD50 unreported 19500mg/kg (19500mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 26, Pg. 921, 1984

supplier list

HangZhou Peak Chemical Co.,Ltd
Tel:+86-571-88233073
Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China
Andexin industrial Co.,Limited
Tel:86-411-39074598
Address: No.98,Shengli road,,Jinzhou district,
Hebei yanxi chemical co., LTD
Tel:86-311-66561638
Address: Zhang zhe, guangzong county, xingtai city, hebei p
Nanjing Bangnuo Biotechnology Co., Ltd
Tel:86-1732-7098554
Address: shuanglong road,jiangning, nanjing,jiangsu
Wuhan Silworld Chemical Co.,Lltd
Tel:86-27-85613400
Address: No.198 jiangjun road ,wuhan,china.
Hangzhou Dayangchem Co., Ltd.
Tel:86-571-88938639
Address: 9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road
Shenzhen Simeiquan Biotechnology Co.Ltd
Tel:86-20-18102838259
Address: Bao'an Bao'an District of Shenzhen City manhole st
Jinan Haohua Industry Co., Ltd.
Tel:0086-531-58773055
Address: No.59 Gongye South RD
AFINE CHEMICALS LIMITED
Tel:86-571-85232161
Address: 6th Floor, Block C, 7th Building, Xigang Xinjie, Xihu Industrial Park, Sandun Town, Hangzhou, China

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