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Home > products > Card-20(22)-enolide,3-[(2,6-dideoxy-4-O-b-D-glucopyranosyl-3-O-methyl-b-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-, (3b,5b)-

Card-20(22)-enolide,3-[(2,6-dideoxy-4-O-b-D-glucopyranosyl-3-O-methyl-b-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-, (3b,5b)- cas no:13137-64-9

Synonyms: Periplocin(6CI,7CI,8CI); Periplocoside

Identification
NameCard-20(22)-enolide,3-[(2,6-dideoxy-4-O-b-D-glucopyranosyl-3-O-methyl-b-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-, (3b,5b)-
CAS13137-64-9
SynonymsPeriplocin(6CI,7CI,8CI); Periplocoside
Molecular FormulaC36H56 O13
Molecular Weight0
Chemical Properties
refractive index1.624
Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 120ug/kg (0.12mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)

GASTROINTESTINAL: NAUSEA OR VOMITING
"Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 193, 1963.
cat LDLo subcutaneous 2500ug/kg (2.5mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)

GASTROINTESTINAL: NAUSEA OR VOMITING
Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 449, 1926.
cat LDLo unreported 121ug/kg (0.121mg/kg)   "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 151, 1963.
frog LDLo subcutaneous 34mg/kg (34mg/kg) CARDIAC: PULSE RATE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 449, 1926.
rabbit LDLo subcutaneous 10mg/kg (10mg/kg) BEHAVIORAL: TREMOR

CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 449, 1926.
rat LDLo subcutaneous 480mg/kg (480mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 449, 1926.

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