Trimetazidine dihydrochloride cas no:13171-25-0
Synonyms: Piperazine, 1-(2,3,4-trimethoxybenzyl)-, dihydrochloride;Kyurinett;Piperazine, 1-((2,3,4-trimethoxyphenyl)methyl)-, dihydrochloride (9CI);1-[(2,3,4-trimethoxyphenyl)methyl]-2,3,5,6-tetrahydropyrazine;1-[(2,3,4-trimethoxyphenyl)methyl]piperazine dihydrochloride;Trimetajust;Lubomail;Piperazine,1-[(2,3,4-trimethoxyphenyl)methyl]-,dihydrochloride;Prestwick_871;S 4004;
NameTrimetazidine dihydrochloride
CAS13171-25-0
SynonymsPiperazine, 1-(2,3,4-trimethoxybenzyl)-, dihydrochloride;Kyurinett;Piperazine, 1-((2,3,4-trimethoxyphenyl)methyl)-, dihydrochloride (9CI);1-[(2,3,4-trimethoxyphenyl)methyl]-2,3,5,6-tetrahydropyrazine;1-[(2,3,4-trimethoxyphenyl)methyl]piperazine dihydrochloride;Trimetajust;Lubomail;Piperazine,1-[(2,3,4-trimethoxyphenyl)methyl]-,dihydrochloride;Prestwick_871;S 4004;
EINECS(EC#)236-117-0
Molecular FormulaC14H24Cl2N2O3
Molecular Weight303.8
Appearancecrystalline solid
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
HazardclassIRRITANT
Hazard Xn:Harmful;
Risk R22;R36/37/38
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TM2976100
- CHEMICAL NAME :
- Piperazine, 1-(2,3,4-trimethoxybenzyl)-,
dihydrochloride
- CAS REGISTRY NUMBER :
- 13171-25-0
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C14-H22-N2-O3.2Cl-H
- MOLECULAR WEIGHT :
- 339.30
- WISWESSER LINE NOTATION :
- T6M DNTJ D1R BO1 CO1 DO1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,527,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 345 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,527,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,527,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1550 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,527,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 305 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #3262852
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 410 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,527,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #3262852
