Cresol cas no:1319-77-3
Synonyms: Cresol (mixed isomers); Methylphenol; Hydroxytoluene; Cresylic acid; Crude phenols; Crude carbolic acid; artoluenol; bacillol; coaltarphenols; cresoli; Cresols
NameCresol
CAS1319-77-3
SynonymsCresol (mixed isomers); Methylphenol; Hydroxytoluene; Cresylic acid; Crude phenols; Crude carbolic acid; artoluenol; bacillol; coaltarphenols; cresoli; Cresols
EINECS(EC#)215-293-2
Molecular FormulaC7H8O
Molecular Weight108.14
Appearancelight yellow to light pink liquid
refractive index1.546
storage tempStore at R.T.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Hazard T:Toxic
Risk R20;R24/25;R34;R52/53;R68
Safety
Hazard Codes of Cresol (CAS NO.1319-77-3):?
T
Risk Statements: 20-24/25-34-52/53-68?
R20: Harmful by inhalation
R24/25: Toxic in contact with skin and if swallowed?
R34: Causes burns
R52/53: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R68: Possible risk of irreversible effects
Safety Statements: 26-36/37/39-45-61?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61: Avoid release to the environment. Refer to special instructions / safety data sheets
RIDADR: UN 2076 6.1/PG 2
WGK Germany: 1
RTECS: GO5950000
F: 8-23?
F 8: Photosensitive
F 23: Sensitive to air
HazardClass: 6.1(a)
PackingGroup: II
A poison by ingestion. Moderately toxic by skin contact. Corrosive to skin and mucous membranes. Systemic poisoning has rarely been reported, but it is possible that absorption may result in damage to the kidneys, liver, and nervous system. The main hazard accompanying its use in industry lies in severe chemical burns and dermatitis.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| human |
LDLo |
oral |
114mg/kg (114mg/kg) |
VASCULAR: OTHER CHANGES |
"Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 404, 1989. |
| man |
TDLo |
oral |
177mg/kg (177mg/kg) |
BLOOD: OTHER HEMOLYSIS WITH OR WITHOUT ANEMIA
BLOOD: OTHER CHANGES |
Canadian Medical Association Journal. Vol. 130, Pg. 1319, 1984.
? |
| mouse |
LD50 |
oral |
760mg/kg (760mg/kg) |
? |
Kyushu Shika Gakkai Zasshi. Journal of the Kyushu Dental Society. Vol. 36, Pg. 932, 1982. |
| rabbit |
LD50 |
skin |
2gm/kg (2000mg/kg) |
? |
Toxicology and Applied Pharmacology. Vol. 42, Pg. 417, 1977.
? |
| rat |
LD50 |
oral |
1454mg/kg (1454mg/kg) |
? |
National Technical Information Service. Vol. PB214-270, |
| women |
TDLo |
oral |
700uL/kg (0.7mL/kg) |
BLOOD: "CHANGES IN SERUM COMPOSITION (E.G., TP, BILIRUBIN, CHOLESTEROL)"
BLOOD: OTHER CHANGES |
American Journal of Emergency Medicine. Vol. 16, Pg. 667, 1998.
? |
1、RTECS#: CAS# 1319-77-3: GO5950000
2、LD50/LC50: RTECS: CAS# 1319-77-3: Oral, mouse: LD50 = 760 mg/kg;Oral, mouse: LD50 = 860 mg/kg;
Oral, rat: LD50 = 1454 mg/kg;Skin, rabbit: LD50 = 2 gm/kg;Skin, rabbit: LD50 = 200 mg/kg;
3、Carcinogenicity: Cresol - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.?
4、Other: See actual entry in RTECS for complete information.
