132539-06-1|10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)-Products Supply

10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)- cas no:132539-06-1

Synonyms: 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine;Olansek;10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)-;Symbyax;Zyprexa (TN);Olanzapine [USAN:INN];2-methyl-4-(4-methylpiperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine;

Identification

Name10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)-
CAS132539-06-1
Synonyms2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine;Olansek;10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)-;Symbyax;Zyprexa (TN);Olanzapine [USAN:INN];2-methyl-4-(4-methylpiperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine;
Molecular FormulaC₁₇H₂₀N₄S
Molecular Weight312.43

Chemical Properties

Appearanceyellowish crystalline powder
refractive index3.3
storage tempStore in original container in a cool dark place.

Safety Data

Safety

Human systemic effects. When heated to decomposition it emits toxic vapors of NO_x and SO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
human	TDLo	oral	16560ug/kg/12 (16.56mg/kg)	BLOOD: "CHANGES IN SERUM COMPOSITION (E.G., TP, BILIRUBIN, CHOLESTEROL)"	Journal of Clinical Psychiatry. Vol. 60, Pg. 767, 1999.
human	TDLo	oral	43mg/kg/30W-I (43mg/kg)	?	Journal of Clinical Pyschopharmacology. Vol. 19, Pg. 273, 1999.
man	LDLo	oral	7067ug/kg (7.067mg/kg)	LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA GASTROINTESTINAL: NAUSEA OR VOMITING LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)"	Journal of Forensic Sciences. Vol. 41, Pg. 1252, 1998.
man	TDLo	oral	2570ug/kg/12D (2.57mg/kg)	AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC	Journal of Clinical Pyschopharmacology. Vol. 19, Pg. 192, 1999.
women	LDLo	oral	30mg/kg/22W-I (30mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION	Annals of Pharmacotherpy. Vol. 33, Pg. 787, 1999.
women	TDLo	oral	400ug/kg (0.4mg/kg)	BEHAVIORAL: REGIDITY VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION	American Journal of Psychiatry. Vol. 156, Pg. 1835, 1999.
women	TDLo	oral	12mg/kg (12mg/kg)	BEHAVIORAL: COMA CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP	Annals of Emergency Medicine. Vol. 32, Pg. 275, 1998.
women	TDLo	oral	12mg/kg/60D-I (12mg/kg)	BEHAVIORAL: TOXIC PSYCHOSIS	Annals of Internal Medicine. Vol. 131, Pg. 72, 1999.

supplier list

Chuming Pharmaceutical Limited: Tel:; Address: 9th Fl.,Garden Building, Jiuzhou Ave. No.1083, Zhuhai,China

Labortorio Dosa S.A: Tel:54 11 4551-4965 / 4554; Address: Girardot 1369 (C1427AKC) City of Buenos Aires,

Beijing Lunarsun Pharmaceutical Co., Ltd.: Tel:+86-(10)-80771328, 80771377; Address: C1-802, Yangguangguangchang, Anli Road No.68, Chaoyang District, Beijing 100101,

Taizhou Intouch Chemical Co. Ltd.: Tel:+86-(576)-88698596; Address: Economic Development Zone, Taizhou, Zhejiang 318000,

Varda Biotech Pvt. Ltd.: Tel:+91-(22)-6693 5686; Address: #110 & 111 Kartik Complex, New Link Road, Andheri (W), Mumbai, Maharashtra 400 053,

Sris Pharmaceuticals: Tel:+91-(40)-23061913; Address: Plot No.2-22-68,G-3,Sailakshmi Residency, Vijayanagar Colony,Vivekananda Nagar, Kukatpally, Hyderabad, Andhra Pradesh 500 072,

Sterling Chemtec: Tel:+971-(50)-5647405; Address: Butena, Sharjah 20196,

Suzhou No.4 Pharmaceutical Factory: Tel:+86-(512)-6533-4311; Address: 171, Baiyang Bay Avenue, Suzhou, Jiangsu,

Sinomax Solutions Co., Ltd.: Tel:+86-(10)-5876-4621; Address: Room 301, Fuli Shuangzi Tower #59, Guangqu Menwai Street Chaoyang District, Beijing,

Tianjin Li Qiang Technology Co., Ltd.: Tel:+86-(22)-2746-2452; Address: 201 Haibin Fifth Tianjin Free Trade Zone, Tianjin 300193,

Ningbo Zhengzhang Chemical Co., Ltd: Tel:+86-21-64303067; Address: 1#Dayun Read

ORCHID CHEMICAL SUPPLIES LTD (OCS): Tel:+86-571-85395792; Address: 607, North Zhongshan Road, Hangzhou 310000 China

Shanghai Youkai Biotechnology Co.ltd: Tel:15900636350; Address: shanghai

Taizhou Shengyu Chemical Co.,Ltd: Tel:+86-576-88861036; Address: Room 1308-1310,Ocean plaza,Jiaojiang

VARDA Biotech (P) Ltd.: Tel:+91(22) 6693 5686; Address: #110 & 111, Kartik complex, New Link Road, Andheri (W), Mumbai - 400 053, INDIA.

10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)- cas no:132539-06-1

Directory

supplier list