132907-72-3|Methanone,(1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-,hydrochloride (1:1)Products Supply

Methanone,(1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-,hydrochloride (1:1) cas no:132907-72-3

Synonyms: Methanone,(1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-5-yl)-,monohydrochloride, (R)-;Methanone,(1-methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]-,monohydrochloride (9CI);(-)-(R)-5-[(1-Methyl-1H-indol-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazolemonohydrochloride;(R)-(-)-Ramosetron hydrochloride;Irribow;Ramosetronhydrochloride;YM 060;

Identification

NameMethanone,(1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-,hydrochloride (1:1)
CAS132907-72-3
SynonymsMethanone,(1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-5-yl)-,monohydrochloride, (R)-;Methanone,(1-methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]-,monohydrochloride (9CI);(-)-(R)-5-[(1-Methyl-1H-indol-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazolemonohydrochloride;(R)-(-)-Ramosetron hydrochloride;Irribow;Ramosetronhydrochloride;YM 060;
Molecular FormulaC₁₇H₁₈ClN₃O
Molecular Weight315.8

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD	intravenous	> 30mg/kg (30mg/kg)	SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE	Oyo Yakuri. Pharmacometrics. Vol. 47, Pg. 117, 1994.
dog	LD	oral	> 60mg/kg (60mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING	Arzneimittel-Forschung. Drug Research. Vol. 45, Pg. 760, 1995.
mouse	LD50	intravenous	90mg/kg (90mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 27, Pg. 652, 1996.
rat	LD50	intravenous	151mg/kg (151mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Oyo Yakuri. Pharmacometrics. Vol. 47, Pg. 105, 1994.
rat	LD50	oral	1264mg/kg (1264mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 41, Pg. 1048, 1999.

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Methanone,(1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-,hydrochloride (1:1) cas no:132907-72-3

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