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Dimethylbenzene cas no:1330-20-7

Synonyms: o-,m-,p-Xylene; m & p-xylene; m-,p-,o-Xylene; Dimethylbenzenes; Dimethylbenzene (mixed isomers); except p-xylene, mixed or all isomers; Socal aquatic solvent 3501; Total xylenes; Xylene; Xylene (o-,m-,p-); Xylene (o-, m-, p-isomers); xylenes; Xylenes? Xylenes (o-, m-, p-isomers); Xylenes (mixed); Xylenes mixed isomers; Xylene (mixed); xylene, mixed or all isomers, except p-; Xylene mixture; Xylene mixture (m-xylene, o-xylene, p-xylene); Xylene mixture (60% m-xylene, 9% o-xylene, 14% p-xylene, 17% ethylbenzene); Xylene, (total); Xylol; Xylene (mixed isomers)

Identification
NameDimethylbenzene
CAS1330-20-7
Synonymso-,m-,p-Xylene; m & p-xylene; m-,p-,o-Xylene; Dimethylbenzenes; Dimethylbenzene (mixed isomers); except p-xylene, mixed or all isomers; Socal aquatic solvent 3501; Total xylenes; Xylene; Xylene (o-,m-,p-); Xylene (o-, m-, p-isomers); xylenes; Xylenes? Xylenes (o-, m-, p-isomers); Xylenes (mixed); Xylenes mixed isomers; Xylene (mixed); xylene, mixed or all isomers, except p-; Xylene mixture; Xylene mixture (m-xylene, o-xylene, p-xylene); Xylene mixture (60% m-xylene, 9% o-xylene, 14% p-xylene, 17% ethylbenzene); Xylene, (total); Xylol; Xylene (mixed isomers)
EINECS(EC#)215-535-7
Molecular FormulaC8H10
Molecular Weight106.16
Chemical Properties
Appearancecolourless liquid
refractive index1.494-1.498
storage tempFlammables area
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass3
Safety Data

Hazard Xn:Harmful;F:Flammable;
Risk R10;R20/21;R36/38
Safety

Moderately toxic by intraperitoneal and subcutaneous routes. Mildly toxic by ingestion and inhalation. An experimental teratogen. Human systemic effects by inhalation: olfactory changes, conjunctiva irritation, and pulmonary changes. Experimental reproductive effects. Mutation data reported. A human eye irritant. An experimental skin and severe eye irritant. Some temporary corneal effects are noted, as well as some conjunctival irritation by instillation (adding drops to the eyes one drop at a time). Irritation can start @ 200 ppm. A very dangerous fire hazard when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes of Xylene (CAS NO.1330-20-7): HarmfulXn,FlammableF
Risk Statements: 10-20/21-36/38 
R10: Flammable. 
R20/21: Harmful by inhalation and in contact with skin. 
R36/38: Irritating to eyes and skin.
Safety Statements: 25 
S25: Avoid contact with eyes.
RIDADR: UN 1307 3/PG 3 


HS Code 29024400

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LCLo inhalation 450ppm (450ppm) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LIVER: FATTY LIVER DEGERATION
Journal of Industrial Hygiene. Vol. 10, Pg. 261, 1928.
guinea pig LDLo intraperitoneal 2gm/kg (2000mg/kg) LIVER: FATTY LIVER DEGERATION American Industrial Hygiene Association Journal. Vol. 35, Pg. 21, 1974.
human LDLo oral 50mg/kg (50mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 883, 1980.
human TCLo inhalation 200ppm (200ppm) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE
Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 282, 1943.
mammal (species unspecified) LC50 inhalation 30gm/m3 (30000mg/m3)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
mammal (species unspecified) LD50 oral 4300mg/kg (4300mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
mammal (species unspecified) LDLo intraperitoneal 2gm/kg (2000mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: IRRITABILITY

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
American Journal of Hygiene. Vol. 7, Pg. 276, 1927.
man LCLo inhalation 10000ppm/6H (10000ppm) BEHAVIORAL: GENERAL ANESTHETIC

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BLOOD: OTHER CHANGES
British Medical Journal. Vol. 3, Pg. 442, 1970.
mouse LD50 intraperitoneal 1548mg/kg (1548mg/kg)   Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 18, Pg. 109, 1960.
mouse LD50 oral 2119mg/kg (2119mg/kg)   EHP, Environmental Health Perspectives. Vol. 106(Suppl,
rabbit LD50 skin > 1700mg/kg (1700mg/kg)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 123, 1974.
rabbit LDLo intravenous 129mg/kg (129mg/kg)   Haematologica. Vol. 58, Pg. 491, 1973.
rat LC50 inhalation 5000ppm/4H (5000ppm)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 123, 1974.
rat LD50 intraperitoneal 2459mg/kg (2459mg/kg)   Environmental Research. Vol. 40, Pg. 411, 1986.
rat LD50 oral 4300mg/kg (4300mg/kg) LIVER: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
AMA Archives of Industrial Health. Vol. 14, Pg. 387, 1956.
rat LD50 subcutaneous 1700mg/kg (1700mg/kg)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 123, 1974.

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