134-63-4|(-)-Lobeline HydrochlorideProducts Supply

(-)-Lobeline Hydrochloride cas no:134-63-4

Synonyms: Lobeline hydrochloride; 2-(6-(2-hydroxy-2-phenethyl)-1-methyl-2-piperidyl)acetophenone hydrochloride; Lobeline HCL

Identification

Name(-)-Lobeline Hydrochloride
CAS134-63-4
SynonymsLobeline hydrochloride; 2-(6-(2-hydroxy-2-phenethyl)-1-methyl-2-piperidyl)acetophenone hydrochloride; Lobeline HCL
EINECS(EC#)205-150-2
Molecular FormulaC22H27NO2?HCl
Molecular Weight373.92

Chemical Properties

AppearanceWhite to off-white solid
refractive index-57.5 ° (C=1, H2O)

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard T:Toxic;
Risk R23/25

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OJ8490100

CHEMICAL NAME :: Lobeline, hydrochloride

CAS REGISTRY NUMBER :: 134-63-4

LAST UPDATED :: 198706

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C22-H27-N-O2.Cl-H

MOLECULAR WEIGHT :: 373.96

WISWESSER LINE NOTATION :: T6NTJ A1 B1YQR& F1VR &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 39900 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,913,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 87500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,913,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7800 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,913,1982

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 163,279,1931

supplier list

Beijing Merson pharmaceutical Co., Ltd.: Tel:; Address: 2nd Floor, No.2 Building, No.14 Houshayu Duan, Jingmi Road ,Shunyi District ,Beijing 101318, P.R.China

Jingzhou Netchem Pharm. & Chem Co., Ltd: Tel:; Address: Oriental Road High-tech Development Zone Jingzhou Hubei Province, P.R.China

Tocris Bioscience: Tel:+1-(800)-421-3701; Address: 16144 Westwoods Business Park, Ellisville, Missouri 63021,

Jingzhou Netchem Pharm.: Tel:+86-(716)-8303176,8303013; Address: Oriental Road High-tech Development Zone, Jingzhou, Hubei 434000,

Beijing Merson Pharmaceutical Technology Development Co., Ltd.: Tel:+86-(10)-80484574, 8048344; Address: 2nd Floor , No. 2 Building , No. 14 Houshayu Duan, Jingmi Road, Shunyi, Beijing 101318,

Hebei Kaixiang Fine Chemical Co., Ltd.: Tel:+86-(318)-688-0666, 013831880321; Address: Shiqunan Chemical park, Shenzhou, Hebei,

A Meryer Chemical Technology Shanghai Company: Tel:+86-755-86170518; Address: Nanshan District

Beijing Merson Pharmaceutical Co., Ltd: Tel:0086-10-80484934 0086-10-80484574/80483447; Address: 2nd Floor , No. 2 Building , No. 14 Houshayu Duan, Jingmi Road ,Shunyi District , Beijing 101318, P.R.China

HangZhou Peak Chemical Co.,Ltd: Tel:+86-571-88233073; Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China

NANTONG PHAETON BIOCHEMICAL TECHNOLOGY CO., LTD.: Tel:+86-513-89076996; Address: No.1568 Shuangtong Rd.

Shijiazhuang Sdyano Fine Chemical Co., Ltd: Tel:86-311-80800737; Address: Room 37-2-2501, Yiyuan Dong Gang Jianshe Nan Stree

Zhejiang Kaili Industrial Co., Ltd.: Tel:86-571-85241926; Address: Block C&D,12/F,Lantian Business Center,No.18 Moganshan Road,Hangzhou,China

Hui Chem Company Limited: Tel:86-21-60542966; Address: Lane 299 Bisheng Rd,Pudong District

Hebei yanxi chemical co., LTD: Tel:86-311-66561638; Address: Zhang zhe, guangzong county, xingtai city, hebei p

Hangzhou J&H Chemical Co., Ltd: Tel:86-571-87396430; Address: No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

(-)-Lobeline Hydrochloride cas no:134-63-4

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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