Benzenemethanol, a-[(1R)-1-(methylamino)ethyl]-,hydrochloride (1:1), (aS)-rel- cas no:134-71-4
Synonyms: Benzenemethanol,a-[(1R)-1-(methylamino)ethyl]-,hydrochloride, (aS)-rel-(9CI);Benzenemethanol, a-[1-(methylamino)ethyl]-,hydrochloride, (R*,S*)-;Ephetonin;Ephetonine;Racephedrine Hydrochloride;dl-Ephedrinehydrochloride;
NameBenzenemethanol, a-[(1R)-1-(methylamino)ethyl]-,hydrochloride (1:1), (aS)-rel-
CAS134-71-4
SynonymsBenzenemethanol,a-[(1R)-1-(methylamino)ethyl]-,hydrochloride, (aS)-rel-(9CI);Benzenemethanol, a-[1-(methylamino)ethyl]-,hydrochloride, (R*,S*)-;Ephetonin;Ephetonine;Racephedrine Hydrochloride;dl-Ephedrinehydrochloride;
EINECS(EC#)205-153-9
Molecular FormulaC10H15 N O . Cl H
Molecular Weight201.72
AppearanceWhite solid
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Hazard Xn: Harmful;
Risk R22;R36/37/38
Safety
Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects: cardiac changes, nausea or vomiting, sweating. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also EPHEDRINE.Safety information of DL-Ephedrine hydrochloride (CAS NO.134-71-4):
Hazard Codes
Xn
Risk Statements 22-36/37/38
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
RIDADR 1544
WGK Germany 3
RTECS KB1750000
HazardClass 6.1(b)
PackingGroup III
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orl-wmn TDLo:1 mg/kg:CAR,GIT,SKN
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 33 (1928),237. |
2. |
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orl-man TDLo:1429 µg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 33 (1928),237. |
3. |
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scu-rat LD50:350 mg/kg
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AEPPAE Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 169 (1933),114. |
4. |
|
orl-mus LD50:700 mg/kg
|
|
JMCMAR Journal of Medicinal Chemistry. 9 (1966),966. |
5. |
|
ipr-mus LD50:254 mg/kg
|
|
PHARAT Pharmazie. 24 (1969),775. |
6. |
|
scu-mus LD50:520 mg/kg
|
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NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. 55 (1959),653. |
7. |
|
ivn-mus LD50:135 mg/kg
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JMCMAR Journal of Medicinal Chemistry. 9 (1966),966. |
8. |
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ivn-rbt LDLo:60 mg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 36 (1929),363. |