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Benzenemethanol, a-[(1R)-1-(methylamino)ethyl]-,hydrochloride (1:1), (aS)-rel- cas no:134-71-4

Synonyms: Benzenemethanol,a-[(1R)-1-(methylamino)ethyl]-,hydrochloride, (aS)-rel-(9CI);Benzenemethanol, a-[1-(methylamino)ethyl]-,hydrochloride, (R*,S*)-;Ephetonin;Ephetonine;Racephedrine Hydrochloride;dl-Ephedrinehydrochloride;

Identification
NameBenzenemethanol, a-[(1R)-1-(methylamino)ethyl]-,hydrochloride (1:1), (aS)-rel-
CAS134-71-4
SynonymsBenzenemethanol,a-[(1R)-1-(methylamino)ethyl]-,hydrochloride, (aS)-rel-(9CI);Benzenemethanol, a-[1-(methylamino)ethyl]-,hydrochloride, (R*,S*)-;Ephetonin;Ephetonine;Racephedrine Hydrochloride;dl-Ephedrinehydrochloride;
EINECS(EC#)205-153-9
Molecular FormulaC10H15 N O . Cl H
Molecular Weight201.72
Chemical Properties
AppearanceWhite solid
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn: Harmful;
Risk R22;R36/37/38
Safety

Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects: cardiac changes, nausea or vomiting, sweating. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also EPHEDRINE.Safety information of DL-Ephedrine hydrochloride (CAS NO.134-71-4):
Hazard Codes  HarmfulXn
Risk Statements  22-36/37/38 
R22:Harmful if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements  26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
RIDADR  1544
WGK Germany  3
RTECS  KB1750000
HazardClass  6.1(b)
PackingGroup  III


Toxicity
1.    

orl-wmn TDLo:1 mg/kg:CAR,GIT,SKN

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 33 (1928),237.
2.    

orl-man TDLo:1429 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 33 (1928),237.
3.    

scu-rat LD50:350 mg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 169 (1933),114.
4.    

orl-mus LD50:700 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 9 (1966),966.
5.    

ipr-mus LD50:254 mg/kg

    PHARAT    Pharmazie. 24 (1969),775.
6.    

scu-mus LD50:520 mg/kg

    NYKZAU    Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. 55 (1959),653.
7.    

ivn-mus LD50:135 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 9 (1966),966.
8.    

ivn-rbt LDLo:60 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 36 (1929),363.

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