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Ephedrine sulfate cas no:134-72-5

Synonyms: Bis[[R-(R*,S*)]-beta-hydroxy-alpha-methylphenethyl methylammonium] sulphate

Identification
NameEphedrine sulfate
CAS134-72-5
SynonymsBis[[R-(R*,S*)]-beta-hydroxy-alpha-methylphenethyl methylammonium] sulphate
EINECS(EC#)205-154-4
Molecular Formula2(C10H15NO).H2O4S
Molecular Weight428.54288
Chemical Properties
Appearancewhite crystalline powder
storage tempKeep containers tightly closed. Store protected from light. Store in a cool, dry area away from incompatible substances.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Poison by intravenous, intraperitoneal, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by intravenous route: increased pulse rate and blood pressure. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also EPHEDRINE.
Hazard Codes: HarmfulXn
Risk Statements about 1-Ephedrine sulfate (CAS No.134-72-5):
R22:Harmful if swallowed.
Safety Statements about 1-Ephedrine sulfate (CAS No.134-72-5):
S22:Do not breathe dust. 
S25:Avoid contact with eyes.
Attention:
1. Storage: Keep containers tightly closed. Store protected from light. Store in a cool, dry area away from incompatible substances.
2. Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Store protected from light.


Toxicity
1.    

ivn-hmn TDLo:1 mg/kg:CVS

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 120 (1927),189.
2.    

orl-rat LD50:404 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),150.
3.    

scu-rat LD50:318 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),150.
4.    

ivn-rat LD50:102 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),150.
5.    

orl-mus LD50:812 mg/kg

    NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-307 ,1986.
6.    

ipr-mus LD50:400 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 28 (1974),227.
7.    

orl-rbt LD50:825 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),150.
8.    

scu-rbt LD50:383 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),150.
9.    

ivn-rbt LD50:73 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),159.

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