1-Propanone,2-(diethylamino)-1-phenyl-, hydrochloride (1:1) cas no:134-80-5

Name1-Propanone,2-(diethylamino)-1-phenyl-, hydrochloride (1:1)
CAS134-80-5
Synonyms1-Propanone,2-(diethylamino)-1-phenyl-, hydrochloride (9CI); Propiophenone,2-(diethylamino)-, hydrochloride (6CI,8CI);1-Phenyl-2-(diethylamino)propanone-1 hydrochloride;2-(Diethylamino)propiophenone hydrochloride; Amfepramon hydrochloride;Amphepramonum hydrochloride; Anfamon; Anorex; Danylen; Diethylpropionhydrochloride; Diethylpropione hydrochloride; Dobesin; Fepranon; Frekentine;Keramik; Keramin; Moderatan; Modulor; Parabolin; Phepranon; Prefamone; Regenon;Regenon hydrochloride; Tenuate; Tenuate hydrochloride; Tenuate-Dospan; Tepanil;Tylinal; a-(Diethylamino)propiophenonehydrochloride; a-Benzoyltriethylaminehydrochloride; a-Benzoyltriethylammoniumchloride
EINECS(EC#)205-156-5
Molecular FormulaC13H19 N O . Cl H
Molecular Weight241.79

Safety

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl, NH₃, and NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	160mg/kg (160mg/kg)		Therapie. Vol. 17, Pg. 373, 1962.
mouse	LD50	intravenous	50mg/kg (50mg/kg)		Acta Pharmacologica et Toxicologica. Vol. 17, Pg. 182, 1960.
mouse	LD50	oral	385mg/kg (385mg/kg)		Therapie. Vol. 17, Pg. 373, 1962.
mouse	LD50	subcutaneous	450mg/kg (450mg/kg)	sense organs and special senses: mydriasis (pupillary dilation): eye behavioral: excitement skin and appendages (skin): hair: other	Acta Pharmaceutica Suecica. Vol. 4, Pg. 37, 1967.
rat	LD50	intraperitoneal	139mg/kg (139mg/kg)	behavioral: excitement	Acta Pharmacologica et Toxicologica. Vol. 17, Pg. 121, 1960.
rat	LD50	oral	400mg/kg (400mg/kg)		Therapie. Vol. 17, Pg. 373, 1962.