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Mecobalamin cas no:13422-55-4

Synonyms: Cobinamide,Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-esterwith 5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole;Algobaz;Co-Methylcobalamin;Cobalamin, Co-methyl-;Hitocobamin M;MeCbl;Methycobal;Methyl cobalamine;Methyl vitamin B12;Methyl-5,6-dimethylbenzimidazolylcobalamin;Methyl-B12;Methylcob(III)alamin;

Identification
NameMecobalamin
CAS13422-55-4
SynonymsCobinamide,Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-esterwith 5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole;Algobaz;Co-Methylcobalamin;Cobalamin, Co-methyl-;Hitocobamin M;MeCbl;Methycobal;Methyl cobalamine;Methyl vitamin B12;Methyl-5,6-dimethylbenzimidazolylcobalamin;Methyl-B12;Methylcob(III)alamin;
EINECS(EC#)236-535-3
Molecular FormulaC63H91CoN13O14P
Molecular Weight1344.38
Chemical Properties
Appearancedark red crystalline powder
storage temp?20°C
Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Questionable carcinogen with experimental neoplastigenic data. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and POx.
Hazard Codes:?IrritantXi
Risk Statements: 36/37/38?
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26?
S24/25: Avoid contact with skin and eyes.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36: Wear suitable protective clothing.
WGK Germany of Mecobalamin (CAS NO.13422-55-4): 2


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD intravenous > 200mg/kg (200mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 22, Pg. 3939, 1988.
mouse LD50 intraperitoneal > 5gm/kg (5000mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970.
mouse LD50 oral > 5gm/kg (5000mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970.
mouse LD50 subcutaneous > 5gm/kg (5000mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970.
rabbit LD50 intravenous > 75mg/kg (75mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970.
rat LD50 intraperitoneal > 5gm/kg (5000mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970.
rat LD50 oral > 5gm/kg (5000mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970.
rat LD50 subcutaneous > 5gm/kg (5000mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970.

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