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Pyrazolo[1,5-a]pyrimidine-6-carboxylicacid, 2-[(diethoxyphosphinothioyl)oxy]-5-methyl-, ethyl ester cas no:13457-18-6

Synonyms: Pyrazolo[1,5-a]pyrimidine-6-carboxylicacid, 2-hydroxy-5-methyl-, ethyl ester, O-ester with O,O-diethylphosphorothioate (8CI);2-(O,O-Diethylthionophosphoryl)-5-methyl-6-carbethoxypyrazolopyrimidine;Afugan; Afugan WP 30; Curamil; Diethyl6-carbethoxy-5-methylpyrazolo[1,5-a]pyrimidin-2-yl phosphorothioate; HOE 2873;Hoechst 2873; Missile; NSC 232671; Pyrazophos

Identification
NamePyrazolo[1,5-a]pyrimidine-6-carboxylicacid, 2-[(diethoxyphosphinothioyl)oxy]-5-methyl-, ethyl ester
CAS13457-18-6
SynonymsPyrazolo[1,5-a]pyrimidine-6-carboxylicacid, 2-hydroxy-5-methyl-, ethyl ester, O-ester with O,O-diethylphosphorothioate (8CI);2-(O,O-Diethylthionophosphoryl)-5-methyl-6-carbethoxypyrazolopyrimidine;Afugan; Afugan WP 30; Curamil; Diethyl6-carbethoxy-5-methylpyrazolo[1,5-a]pyrimidin-2-yl phosphorothioate; HOE 2873;Hoechst 2873; Missile; NSC 232671; Pyrazophos
EINECS(EC#)236-656-1
Molecular FormulaC14H20 N3 O5 P S
Molecular Weight373.36
Chemical Properties
refractive index1.595
storage tempAPPROX 4°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn: Harmful;N: Dangerous for the environment;
Risk 20/22-50/53
Safety Hazard Codes Xn,NRisk Statements 20/22-50/53Safety Statements 36/37-46-60-61RIDADR 2783RTECS TF2035000HazardClass 6.1(b)PackingGroup III

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TF2035000
CHEMICAL NAME :
Phosphorothioic acid, O,O-diethyl ester, O-ester with (6-ethoxycarbonyl-5-methyl) pyrazolo(1,5-a)pyrimidin-2-ol
CAS REGISTRY NUMBER :
13457-18-6
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C14-H20-N3-O5-P-S
MOLECULAR WEIGHT :
373.40
WISWESSER LINE NOTATION :
T56 ANN FNJ COPS&O2&O2 G1 HVO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
218 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KHZDAN Khigiena i Zdraveopazvane. Hygiene and Sanitation. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.9- 1966- Volume(issue)/page/year: 23,538,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,734,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
435 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,1266,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
118 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,734,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
184 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,1266,1989 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 53,99,1974

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