135-07-9|2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-, 1,1-dioxideProducts Supply

2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-, 1,1-dioxide cas no:135-07-9

Synonyms: 6-Chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide;6-Chloro-3-chloromethyl-2-methyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine1,1-dioxide;6-Chloro-3-chloromethyl-3,4-dihydro-2-methyl-7-sulfamoyl-1,2,4-benzothiadiazine1,1-dioxide;6-Chloro-3-chloromethyl-3,4-dihydro-2-methyl-7-sulfamoyl-2H-1,2,4-benzothiadiazine1,1-dioxide;Aquatensen;Ciba 7272-Su;Duretic;Enduron;Enduronum;Eutron;Methyclothiazid;Methyclothiazide;Methycyclothiazide;Methylcyclothiazide;NSC110431;Naturon;

Identification

Name2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-, 1,1-dioxide
CAS135-07-9
Synonyms6-Chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide;6-Chloro-3-chloromethyl-2-methyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine1,1-dioxide;6-Chloro-3-chloromethyl-3,4-dihydro-2-methyl-7-sulfamoyl-1,2,4-benzothiadiazine1,1-dioxide;6-Chloro-3-chloromethyl-3,4-dihydro-2-methyl-7-sulfamoyl-2H-1,2,4-benzothiadiazine1,1-dioxide;Aquatensen;Ciba 7272-Su;Duretic;Enduron;Enduronum;Eutron;Methyclothiazid;Methyclothiazide;Methycyclothiazide;Methylcyclothiazide;NSC110431;Naturon;
EINECS(EC#)205-172-2
Molecular FormulaC₉H₁₁Cl₂N₃O₄S₂
Molecular Weight360.23

Chemical Properties

Appearancewhite crystal powder
refractive index1.606

Safety Data

Safety

Poison by intravenous route. Moderately toxic by intraperitoneal route. Mutation data reported. An FDA proprietary drug. When heated to decomposition it emits very toxic fumes of SO_x, NO_x, and Cl⁻.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intraperitoneal	870mg/kg (870mg/kg)	"Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 77, 1969.
mouse	LD50	intravenous	400mg/kg (400mg/kg)	"Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 77, 1969.
mouse	LD50	oral	> 10gm/kg (10000mg/kg)	Drugs in Japan Vol. 6, Pg. 825, 1982.
rat	LD50	intraperitoneal	2gm/kg (2000mg/kg)	"Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 77, 1969.
rat	LD50	oral	> 4gm/kg (4000mg/kg)	Drugs in Japan Vol. 6, Pg. 825, 1982.

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2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-, 1,1-dioxide cas no:135-07-9

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