136-40-3|PHENAZOPYRIDINE HYDROCHLORIDEProducts Supply

PHENAZOPYRIDINE HYDROCHLORIDE cas no:136-40-3

Synonyms: BISTERIL ; MALLOPHENE ; 3-PHENYLAZO-2,6-DIAMINOPYRIDINE HYDROCHLORIDE ; 3-PHENYLAZO-2,6-DIAMINOPYRIDINE MONOHYDROCHLORIDE ; 3-(PHENYLAZO)-2,6-PYRIDINEDIAMINE, MONOHYDROCHLORIDE ; 3-BENZENEAZO-2,6-DIAMINOPYRIDINE MONOHYDROCHLORIDE ; 2,6-DIAMINO-3-[PHENYLAZO]PYRIDINE HYDROCHLORIDE ; 2,6-DIAMINO-3-(PHENYLAZO)PYRIDINE MONOHYDROCHLORIDE ; PHENYLAZODIAMINOPYRIDINE HYDROCHLORIDE ; PHENAZODINE ; PHENAZOPYRIDINE HCL ; PYRIDACIL;

Identification

NamePHENAZOPYRIDINE HYDROCHLORIDE
CAS136-40-3
SynonymsBISTERIL ; MALLOPHENE ; 3-PHENYLAZO-2,6-DIAMINOPYRIDINE HYDROCHLORIDE ; 3-PHENYLAZO-2,6-DIAMINOPYRIDINE MONOHYDROCHLORIDE ; 3-(PHENYLAZO)-2,6-PYRIDINEDIAMINE, MONOHYDROCHLORIDE ; 3-BENZENEAZO-2,6-DIAMINOPYRIDINE MONOHYDROCHLORIDE ; 2,6-DIAMINO-3-[PHENYLAZO]PYRIDINE HYDROCHLORIDE ; 2,6-DIAMINO-3-(PHENYLAZO)PYRIDINE MONOHYDROCHLORIDE ; PHENYLAZODIAMINOPYRIDINE HYDROCHLORIDE ; PHENAZODINE ; PHENAZOPYRIDINE HCL ; PYRIDACIL;
EINECS(EC#)205-243-8
Molecular FormulaC11H11N5?HCl;C11H12ClN5
Molecular Weight249.7

Chemical Properties

Appearancebrick-red crystals
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Safety Data

Hazard Xn:Harmful;
Risk R22;R36/37/38;R40
Safety

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. A poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: somnolence, cyanosis, diarrhea, nausea or vomiting, anuria or decreased urine volume, normocytic anemia, methemoglobinemia-carboxyhemoglobinemia, dehydration, changes in blood sodium levels. Mutation data reported. When heated to decomposition it emits very toxic fumes of NO_x and HCl.
Hazard Codes:? Harmful Xn, Corrosive C
Risk Statements: 22-36/37/38-40-34
R22: Harmful if swallowed.?
R36/37/38: Irritating to eyes, respiratory system and skin.?
R34: Causes burns.?
R40: Limited evidence of a carcinogenic effect.
Safety Statements of Phenazopyridine hydrochloride (CAS NO.136-40-3): 26-36/37-45-36/37/39-27?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37: Wear suitable protective clothing and gloves.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S27: Take off immediately all contaminated clothing.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
child	TDLo	oral	35mg/kg (35mg/kg)	VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION KIDNEY, URETER, AND BLADDER: HEMATURIA BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN	American Journal of Diseases of Children. Vol. 117, Pg. 369, 1969. ?
child	TDLo	oral	125mg/kg (125mg/kg)	LUNGS, THORAX, OR RESPIRATION: CYANOSIS BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN BLOOD: OTHER HEMOLYSIS WITH OR WITHOUT ANEMIA	Clinical Pediatrics Vol. 10, Pg. 537, 1971. ?
child	TDLo	oral	400mg/kg (400mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS	American Journal of Diseases of Children. Vol. 110, Pg. 105, 1965. ?
man	TDLo	oral	86mg/kg/10D-I (86mg/kg)	SPINAL CORD: INFLAMMATORY CHANGES	Annals of Internal Medicine. Vol. 106, Pg. 164, 1987.
man	TDLo	oral	114mg/kg (114mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED	Human Toxicology. Vol. 2, Pg. 539, 1983. ?
mouse	LD50	intravenous	180mg/kg (180mg/kg)	?	U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04014,
rat	LD50	oral	472mg/kg (472mg/kg)	?	Toxicology and Applied Pharmacology. Vol. 1, Pg. 42, 1959.
rat	LDLo	intraperitoneal	200mg/kg (200mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI	Journal of Pharmacology and Experimental Therapeutics. Vol. 51, Pg. 200, 1934.
women	TDLo	oral	34mg/kg (34mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED	Annals of Internal Medicine. Vol. 72, Pg. 89, 1970. ?
women	TDLo	oral	140mg/kg (140mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING BLOOD: NORMOCYTIC ANEMIA	Canadian Medical Association Journal. Vol. 91, Pg. 756, 1964.

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suchem pharma co.,limited: Tel:86-57781172668; Address: wenzhou, China

PHENAZOPYRIDINE HYDROCHLORIDE cas no:136-40-3

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