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2-Propanol,1-[(1-methylethyl)amino]-3-[2-(2-propen-1-yl)phenoxy]- cas no:13655-52-2

Synonyms: 2-Propanol,1-(o-allylphenoxy)-3-(isopropylamino)- (8CI); 2-Propanol,1-[(1-methylethyl)amino]-3-[2-(2-propenyl)phenoxy]- (9CI); (RS)-Alprenolol; (?à)-Alprenolol;1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol;1-Isopropylamino-3-(2-allyl)phenoxypropan-2-ol; Alpheprol; Alprenolol;dl-Alprenolol

Identification
Name2-Propanol,1-[(1-methylethyl)amino]-3-[2-(2-propen-1-yl)phenoxy]-
CAS13655-52-2
Synonyms2-Propanol,1-(o-allylphenoxy)-3-(isopropylamino)- (8CI); 2-Propanol,1-[(1-methylethyl)amino]-3-[2-(2-propenyl)phenoxy]- (9CI); (RS)-Alprenolol; (?à)-Alprenolol;1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol;1-Isopropylamino-3-(2-allyl)phenoxypropan-2-ol; Alpheprol; Alprenolol;dl-Alprenolol
EINECS(EC#)237-140-9
Molecular FormulaC15H23 N O2
Molecular Weight249.39
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T: Toxic;
Risk R23/24/25
Safety

A human poison by ingestion. Poison experimentally by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. See also ALLYL COMPOUNDS. A beta-adrenergic blocker.
Hazard Codes: Toxic
Risk Statements: 23/24/25-43 
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed. 
R43: May cause sensitization by skin contact.
Safety Statements:  36/37/39-45
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III


Toxicity

1.    

orl-wmn LDLo:210 mg/kg

    UGLAAD    Ugeskrift for Laeger. 139 (1977),2817.
2.    

ipr-mus LD50:90 mg/kg

    EJMCA5    European Journal of Medicinal Chemistry. Chimie Therapeutique. 18 (1983),151.
3.    

ivn-mus LD50:20 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1022.
4.    

orl-mam LD50:184 mg/kg

    PCJOAU    Pharmaceutical Chemistry Journal (English Translation). 8 (1974),137.
5.    

ipr-mam LD50:102 mg/kg

    PCJOAU    Pharmaceutical Chemistry Journal (English

supplier list

Nanjing DebioChem Co., Ltd.
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Tel:010-86181995
Address: Beijing TongZhou District
Tianjin Harmony Technology Development Co., Ltd.
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Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

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