136572-09-3|Irinotecan hydrochloride trihydrateProducts Supply

Irinotecan hydrochloride trihydrate cas no:136572-09-3

Synonyms: [1,4'-Bipiperidine]-1'-carboxylicacid,(4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-ylester, monohydrochloride, trihydrate (9CI);[1,4'-Bipiperidine]-1'-carboxylicacid,4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-ylester, monohydrochloride, trihydrate, (S)-;Irinotecan hydrochloridehydrate;

Identification

NameIrinotecan hydrochloride trihydrate
CAS136572-09-3
Synonyms[1,4'-Bipiperidine]-1'-carboxylicacid,(4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-ylester, monohydrochloride, trihydrate (9CI);[1,4'-Bipiperidine]-1'-carboxylicacid,4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-ylester, monohydrochloride, trihydrate, (S)-;Irinotecan hydrochloridehydrate;
Molecular FormulaC₃₃H₄₅ClN₄O₉
Molecular Weight677.19

Chemical Properties

AppearancePale yellow to yellow crystalline powder

Safety Data

Safety

A poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NO_x, HCl, and Cl^?.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	40mg/kg (40mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 953, 1995.
mouse	LD50	intravenous	132mg/kg (132mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 953, 1995.
mouse	LD50	oral	1045mg/kg (1045mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 953, 1995.
rat	LD50	intravenous	83600ug/kg (83.6mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 953, 1995.
rat	LD50	oral	867mg/kg (867mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 953, 1995.

supplier list

Tianjin Harmony Technology Development Co., Ltd.: Tel:; Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

Shanghai Mingdou Chemical Co.,Ltd: Tel:86-21-52912919; Address: Floor 12th, Zhenyuan Building ,No 2052.North Zhongshan Road, Shanghai,China

Beijing Ribio Biotech Co.,Ltd.: Tel:; Address: XinCaiLiao ChuangYe Building,BeiJing China

Techwin bio.&Pharm.Products Co.,Ltd.: Tel:; Address: 409 Zhongzhen Bldg.,No.68 Luofang Road,Shenzhen,Guangdong,China.

ShangHai PuYi Chemical Co.,Ltd: Tel:86-21-57687505; Address: 3F,Building 11,No.201 MinYi Road,Songjiang District,201612,ShangHai,China

Dongyang Honsen Co., Limited: Tel:+86-579-86846643; Address: Geshan Town, Dongyang City, Zhejiang Province

J.INC.: Tel:+91 79 30903703; Address: 303, 3rd Floor, Royale Manor, Law Garden,Ellisbridge, Ahmedabad - 380006,Gujarat, India

Hetero Drugs Ltd.,: Tel:+91-(40)-23704923; Address: H.No. 8-3-166/7/1, Erragadda, Hyderabad, Andhra Pradesh 500 018,

Aanjaneya Biotech Private Limited: Tel:+91-(22)-25243678; Address: Aanjaneya House, No 34, Postal Colony, Chembur, Mumbai, Maharashtra 400071,

Aceto Corporation: Tel:+1-(516)-627-6000; Address: One Hallow Lane, Lake Success, New York 11042-1215,

LC Laboratories: Tel:+1-(781)-937-0777; Address: 165 New Boston Street, Woburn, Massachusetts 01801,

Triomphe Fine Chemistry Co., Ltd.: Tel:+86-(21)-65127018; Address: Shanghai Songjiang Industrial Park, Shanghai 200080,

Shanghai Richem International Co., Ltd.: Tel:+86-(21)-31263688; Address: Room 603, Golden Eagle Mansion A, No.1518 Minsheng Road, Pudong, Shanghai 200135,

Sino-Future Bio-tech Co., Ltd.: Tel:+86-(29)-83182005; Address: No. 18, Dianzi 1Road, Xi'an, Shaanxi 710014,

Taizhou Creating Chemical Co. ,Ltd.: Tel:+86-(576)-88827176,88820069; Address: B Suite 12F,JiangbinBuilding,Jiaojiang, Taizhou, Zhejiang,

Irinotecan hydrochloride trihydrate cas no:136572-09-3

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