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Tetramethylthiuram disulfide cas no:137-26-8

Synonyms: bis(dimethylthiocarbamyl) disulphide; thiram; thiram (tmtd); tmtd; tetramethylthiuram disulphide; tetramethyl thiuram disulfide; 1,1'-dithiobis(n,n-dimethylthio-formamid; 1,1'-dithiobis(n,n-dimethylthioformamide); aapirol; accel tmt; accelerator t; accelerator thiuram; acceleratort; acceleratorthiuram; acceleratortmtd; aceto tetd; acetotetd; alpha,alpha'-dithiobis(dimethylthio)formamide; anles; arasan; arasan 42s; arasan 70; arasan 70-s red; arasan 75; arasan42-s

Identification
NameTetramethylthiuram disulfide
CAS137-26-8
Synonymsbis(dimethylthiocarbamyl) disulphide; thiram; thiram (tmtd); tmtd; tetramethylthiuram disulphide; tetramethyl thiuram disulfide; 1,1'-dithiobis(n,n-dimethylthio-formamid; 1,1'-dithiobis(n,n-dimethylthioformamide); aapirol; accel tmt; accelerator t; accelerator thiuram; acceleratort; acceleratorthiuram; acceleratortmtd; aceto tetd; acetotetd; alpha,alpha'-dithiobis(dimethylthio)formamide; anles; arasan; arasan 42s; arasan 70; arasan 70-s red; arasan 75; arasan42-s
EINECS(EC#)205-286-2
Molecular FormulaC6H12N2S4
Molecular Weight240.41
Chemical Properties
Appearancewhite to off white powder
refractive index1.677
storage temp0-6°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass9
Safety Data

Hazard Xn:Harmful
Risk R20/22;R36/38;R43;R48/22;R50/53
Safety

Safety Information of Tetramethylthiuram disulfide (CAS NO. 137-26-8):
Hazard Codes: Xn?Harmful,N?Dangerous
Risk Statements: 20/22-36/38-43-48/22-50/53
R20/22:Harmful by inhalation and if swallowed
R36/38:Irritating to eyes and skin
R43:May cause sensitization by skin contact
R48/22:Harmful: danger of serious damage to health by prolonged exposure if swallowed
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Statements: 26-36/37-60-61
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37:Wear suitable protective clothing and gloves
S60:This material and its container must be disposed of as hazardous waste
S61:Avoid release to the environment. Refer to special instructions / safety data sheets
RIDADR: UN 2771/2811
WGK Germany: 3
RTECS: JO1400000
HazardClass: 9
PackingGroup: III
HS Code: 29303000


HS Code 29303000

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 300mg/kg (300mg/kg) ? Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
cat LDLo oral 230mg/kg (230mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: ATAXIA
BEHAVIORAL: ANALGESIA
Journal of Pharmacology and Experimental Therapeutics. Vol. 17, Pg. 349, 1921.
chicken LD50 unreported 840mg/kg (840mg/kg) ? Veterinariya. Veterinary Science. Vol. 54(2), Pg. 70, 1978.
domestic animals - goat/sheep LD50 unreported 225mg/kg (225mg/kg) ? Veterinariya. Veterinary Science. Vol. 54(2), Pg. 70, 1978.
human TCLo inhalation 30ug/m3/5Y-I (0.03mg/m3) SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE
CARDIAC: OTHER CHANGES
LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI
Vrachebnoe Delo. Medical Practice. Vol. (10), Pg. 136, 1971.
mammal (species unspecified) LD50 unreported 400mg/kg (400mg/kg) ? Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(5), Pg. 29, 1980.
mouse LD50 intraperitoneal 70mg/kg (70mg/kg) ? Drugs in Japan Vol. 6, Pg. 566, 1982.
mouse LD50 oral 1250mg/kg (1250mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 6(7), Pg. 28, 1962.
mouse LD50 subcutaneous 1109mg/kg (1109mg/kg) ? Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 15, Pg. 507, 1990.
mouse LD50 unreported 1150mg/kg (1150mg/kg) ? Kobunshi Kako. Polymer Applications. Vol. 26, Pg. 358, 1977.
rabbit LD50 oral 210mg/kg (210mg/kg) ? Kobunshi Kako. Polymer Applications. Vol. 26, Pg. 358, 1977.
rabbit LD50 unreported 210mg/kg (210mg/kg) ? Veterinariya. Veterinary Science. Vol. 54(2), Pg. 70, 1978.
rabbit LDLo skin 1gm/kg (1000mg/kg) ? "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 110, 1982.
rat LC50 inhalation 500mg/m3/4H (500mg/m3) ? "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1027, 1986.
rat LD50 intraperitoneal 138mg/kg (138mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Journal de Pharmacologie. Vol. 9, Pg. 35, 1978.
rat LD50 oral 560mg/kg (560mg/kg) ? Toxicology and Applied Pharmacology. Vol. 11, Pg. 546, 1967.
rat LD50 subcutaneous 646mg/kg (646mg/kg) ? Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 15, Pg. 507, 1990.
rat LD50 unreported 740mg/kg (740mg/kg) ? Kobunshi Kako. Polymer Applications. Vol. 26, Pg. 358, 1977.
rat LDLo skin 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 15(Suppl,

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