Octanoic acid,6-(acetylthio)-8-[[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-(2-hydroxyethyl)-1-propen-1-yl]dithio]-,methyl ester cas no:137-86-0

NameOctanoic acid,6-(acetylthio)-8-[[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-(2-hydroxyethyl)-1-propen-1-yl]dithio]-,methyl ester
CAS137-86-0
SynonymsOctanoic acid,6-(acetylthio)-8-[[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-(2-hydroxyethyl)-1-propenyl]dithio]-,methyl ester (9CI); Gerostop; Neuvitan; Octotiamine;S-(3-Acetylthio-7-carbomethoxyheptylthio)thiamine; TATD; Thiamine 8-(methyl6-acetyldihydrothioctate) disulfide;Thiamine(7-methoxycarbonyl-3-acetylthioheptyl) disulfide
Molecular FormulaC23H36 N4 O5 S3
Molecular Weight544.81

refractive index1.595

Safety

Poison by intravenous route. Moderately toxic by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of SO_x and NO_x. See also ESTERS.

1.		orl-mus LD50:2590 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),159.
2.		ipr-mus LD50:522 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),159.
3.		scu-mus LD50:1410 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),159.
4.		ivn-mus LD50:399 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),159.