n-Butyl Lactate cas no:138-22-7

Namen-Butyl Lactate
CAS138-22-7
Synonyms2-Propanoic Acid; Butyl 2-hydroxypropanoate; Butyl alpha-Hydroxypropionate; Butyl Lactate; Lactic Acid Butyl Ester;
EINECS(EC#)205-316-4
Molecular FormulaC7H14O3
Molecular Weight146.18

AppearanceA clear colorless liquid with a mild odor.
refractive index1.42-1.422
storage tempKeep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Hazardclass3

Hazard Xi:Irritant;
Risk R36/37/38

CHEMICAL IDENTIFICATION

RTECS NUMBER :

OD4025000

CHEMICAL NAME :

Lactic acid, butyl ester

CAS REGISTRY NUMBER :

138-22-7

BEILSTEIN REFERENCE NO. :

1721597

LAST UPDATED :

199712

DATA ITEMS CITED :

21

MOLECULAR FORMULA :

C7-H14-O3

MOLECULAR WEIGHT :

146.21

WISWESSER LINE NOTATION :

QY1&VO4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,727,1979 ** ACUTE TOXICITY DATA **

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>5 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,727,1979

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

12 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,15,1974

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

11 gm/kg

TOXIC EFFECTS :

Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :

FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,727,1979

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

>5 gm/kg

REFERENCE :

FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,727,1979 *** REVIEWS *** ACGIH TLV-TWA 30 mg/m3 (5 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1 ppm (5 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,33,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 5 ppm (25 mg/m3) JAN 1993 OEL-BELGIUM:TWA 5 ppm (30 mg/m3) JAN 1993 OEL-DENMARK:TWA 5 ppm (25 mg/m3) JAN 1993 OEL-FINLAND:TWA 1 ppm (6 mg/m3);STEL 3 ppm (18 mg/m3) JAN 1993 OEL-FRANCE:TWA 5 ppm (25 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 5 ppm (25 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 5 ppm (30 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 5 ppm (25 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO n-BUTYL LACTATE-air:10H TWA 5 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1128 No. of Facilities: 242 (estimated) No. of Industries: 8 No. of Occupations: 10 No. of Employees: 3107 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1128 No. of Facilities: 170 (estimated) No. of Industries: 9 No. of Occupations: 15 No. of Employees: 5342 (estimated) No. of Female Employees: 1381 (estimated)