Ethane,2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro- cas no:13838-16-9
Synonyms: Ether,2-chloro-1,1,2-trifluoroethyl difluoromethyl (8CI); (?à)-Enflurane;2-Chloro-1,1,2-trifluoro-1-difluoromethoxyethane; 2-Chloro-1,1,2-trifluoroethyldifluoromethyl ether; 347; Alyrane; Anesthetic Compound No. 347; Compound 347;Efrane; Enflurane; Ethrane; Methylflurether; NSC 115944; Ohio 347; R-E 235ca2
NameEthane,2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-
CAS13838-16-9
SynonymsEther,2-chloro-1,1,2-trifluoroethyl difluoromethyl (8CI); (?à)-Enflurane;2-Chloro-1,1,2-trifluoro-1-difluoromethoxyethane; 2-Chloro-1,1,2-trifluoroethyldifluoromethyl ether; 347; Alyrane; Anesthetic Compound No. 347; Compound 347;Efrane; Enflurane; Ethrane; Methylflurether; NSC 115944; Ohio 347; R-E 235ca2
EINECS(EC#)237-553-4
Molecular FormulaC3H2 Cl F5 O
Molecular Weight184.4921
refractive index1.303
Hazard Volatile with anesthetic properties, but nonflammable. TLV: 75 ppm; not classifiable as a human carcinogen.
Risk R36
Safety
Mildly toxic by inhalation, ingestion, and subcutaneous routes. Human systemic effects by inhalation: decreased urine volume or anuria. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. An eye irritant. Questionable carcinogen with experimental carcinogenic data. An anesthetic. When heated to decomposition it emits very toxic fumes of F− and Cl−. See also ETHERS.Safety information of 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane (CAS NO.13838-16-9):
Hazard Codes 
F,
T
Risk Statements
36 Irritating to the eyes
Safety Statements
23 Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer)
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36 Wear suitable protective clothing
RTECS KN6800000
Hazard Note Flammable/Toxic
| 1. |
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eye-rbt 100 mg MOD
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FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. 35 (1976),729. |
| 2. |
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cyt-hmn:lyms 1000 ppm
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ENVRAL Environmental Research. 12 (1976),366. |
| 3. |
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cyt-mus:fbr 1000 ppm
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ENVRAL Environmental Research. 12 (1976),366. |
| 4. |
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ihl-hmn TCLo:1 pph/6H
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ANESAV Anesthesiology. 45 (1976),557. |
| 5. |
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orl-rat LD50:5450 mg/kg
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DRUGAY Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),143. |
| 6. |
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ihl-rat LC50:14,000 ppm/3H
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IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 12 (1981),668. |
| 7. |
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ipr-rat LD50:6 g/kg
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DRUGAY Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),143. |
| 8. |
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scu-rat LD50:19,500 mg/kg
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YKYUA6 Yakkyoku. Pharmacy. 32 (1981),491. |
| 9. |
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orl-mus LD50:5 g/kg
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DRUGAY Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),143. |
| 10. |
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ihl-mus LC50:8100 ppm/3H
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IYKEDH Iyakuhin Kenkyu. Study of |
